Date published: 2026-4-14

1-800-457-3801

SCBT Portrait Logo
Seach Input

Spectinomycin sulfate tetrahydrate (CAS 64058-48-6)

5.0(1)
Write a reviewAsk a question

Alternate Names:
Trobicin sulfate
CAS Number:
64058-48-6
Molecular Weight:
502.48
Molecular Formula:
C14H24N2O7•H2SO44H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Spectinomycin sulfate tetrahydrate, an antibiotic compound, finds utility in combating specific bacterial infections. It derives from spectinomycin, an antibiotic naturally produced by Streptomyces spectabilis. Exhibiting efficacy against both gram-positive and gram-negative bacteria, Spectinomycin sulfate tetrahydrate operates by impeding protein synthesis within bacterial cells. It accomplishes this by binding to the 30S ribosomal subunit, thereby obstructing the attachment of aminoacyl-tRNA to the A site of the ribosome. As a result, the formation of peptide bonds, essential for protein synthesis, is prevented. This distinctive mechanism of action contributes to the compound′s effectiveness in combating bacterial infections.


Spectinomycin sulfate tetrahydrate (CAS 64058-48-6) References

  1. Effect of lincomycin and spectinomycin on swine dysentery.  |  DeGeeter, MJ. and Harris, DL. 1975. J Anim Sci. 41: 1333-8. PMID: 127771
  2. A new antibiotic combination for frozen bovine semen. 2. Evaluation of seminal quality.  |  Lorton, SP., et al. 1988. Theriogenology. 29: 593-607. PMID: 16726382
  3. Efficacy of turkey herpesvirus vaccine when administered simultaneously with fowl pox vaccine.  |  Eidson, CS., et al. 1975. Poult Sci. 54: 1975-81. PMID: 180502
  4. Vaccination of chickens against Marek's disease with the turkey herpesvirus vaccine using a pneumatic vaccinator.  |  Eidson, CS. and Kleven, SH. 1976. Poult Sci. 55: 960-9. PMID: 180512
  5. Effect of farm type on within-herd Salmonella prevalence, serovar distribution, and antimicrobial resistance.  |  Rasschaert, G., et al. 2012. J Food Prot. 75: 859-66. PMID: 22564934
  6. Sperm DNA fragmentation and morphological degeneration in chilled elephant (Elephas maximus and Loxodonta Africana) semen collected by transrectal massage.  |  O'Brien, JK., et al. 2013. Andrology. 1: 387-400. PMID: 23536498
  7. Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. I. Inhibition of expression of alloantigen-activated suppressor cells, as well as induction of alloreactivity.  |  Yoshimura, N., et al. 1989. Transplantation. 47: 351-6. PMID: 2465592
  8. Development of high performance liquid chromatography methods with charged aerosol detection for the determination of lincomycin, spectinomycin and its impurities in pharmaceutical products.  |  Stypulkowska, K., et al. 2015. J Pharm Biomed Anal. 112: 8-14. PMID: 25938473
  9. Sequestration of bovine seminal plasma proteins by different assemblies of phosphatidylcholine: A new technical approach.  |  Le Guillou, J., et al. 2016. Colloids Surf B Biointerfaces. 140: 523-530. PMID: 26628332
  10. Derivatization of secondary amines with 2-naphthalene-sulfonyl chloride for high-performance liquid chromatographic analysis of spectinomycin.  |  Tsuji, K. and Jenkins, KM. 1985. J Chromatogr. 333: 365-80. PMID: 2932457
  11. Chrysanthemum requires short-day repeats for anthesis: Gradual CsFTL3 induction through a feedback loop under short-day conditions.  |  Nakano, Y., et al. 2019. Plant Sci. 283: 247-255. PMID: 31128695
  12. In vivo and in vitro studies on the effect of gentamicin sulfate on the efficacy of the turkey herpesvirus vaccine.  |  Eidson, CS., et al. 1978. Poult Sci. 57: 1519-25. PMID: 751032
  13. Dissemination of Salmonella serotypes from raw feed ingredients to chicken carcases.  |  MacKenzie, MA. and Bains, BS. 1976. Poult Sci. 55: 957-60. PMID: 935061

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Spectinomycin sulfate tetrahydrate, 1 g

sc-286778
1 g
$66.00

Spectinomycin sulfate tetrahydrate, 5 g

sc-286778A
5 g
$107.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical is supplied as a white powder. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2018-04-03
  • y_2026, m_4, d_9, h_7CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_286778, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 116ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from IsclaIscla, I. et al. (PubMed 25205267) reported that the potency of the antibiotic Spectinomycin is dependent on MscL channel expression. -SCBT Publication Review
Date published: 2015-02-19
  • y_2026, m_4, d_9, h_7
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_286778, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
Spectinomycin sulfate tetrahydrate is rated 5.0 out of 5 by 1.
  • y_2026, m_4, d_9, h_7
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_286778, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 106ms
  • REVIEWS, PRODUCT