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Sparteine Sulfate (CAS 299-39-8)

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CAS Number:
299-39-8
Molecular Weight:
332.46
Molecular Formula:
C15H28N2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sparteine sulfate, an alkaloid derived from the seeds of the Spartina genus of plants. Sparteine sulfate′s interactions with a range of receptors and enzymes have garnered considerable interest. While the precise mechanism of action of Sparteine sulfate remains elusive, it is believed to engage with various receptors and enzymes, thereby eliciting its effects. Interactions with muscarinic, nicotinic, and opioid receptors, as well as enzymes like acetylcholinesterase and monoamine oxidase.


Sparteine Sulfate (CAS 299-39-8) References

  1. Continuous intrauterine pressure recordings in the evaluation of sparteine sulfate.  |  STANDER, RW., et al. 1963. Am J Obstet Gynecol. 86: 281-7. PMID: 13983361
  2. Experience in the use of sparteine sulfate as an oxytocic.  |  SAVEL, LE., et al. 1962. J Newark Beth Isr Hosp. 13: 184-8. PMID: 14497594
  3. Differential effects of quinidine on the disposition of nifedipine, sparteine, and mephenytoin in humans.  |  Schellens, JH., et al. 1991. Clin Pharmacol Ther. 50: 520-8. PMID: 1934865
  4. Interactions of alkaloids with galeal chemosensory cells of colorado potato beetle.  |  Mitchell, BK. 1987. J Chem Ecol. 13: 2009-22. PMID: 24301471
  5. Steady-state plasma levels of E- and Z-10-OH-nortriptyline in nortriptyline-treated patients: significance of concurrent medication and the sparteine oxidation phenotype.  |  Gram, LF., et al. 1989. Ther Drug Monit. 11: 508-14. PMID: 2815225
  6. Sparteine sulfate prevalently stimulates B rather than A cell secretion in obese subjects.  |  Paolisso, G., et al. 1988. Horm Metab Res. 20: 658-9. PMID: 3065201
  7. Search for Therapeutic Agents for Cardiac Arrest Using a Drug Discovery Tool and Large-Scale Medical Information Database.  |  Zamami, Y., et al. 2019. Front Pharmacol. 10: 1257. PMID: 31780928
  8. Molecular Logic and Evolution of Bitter Taste in Drosophila.  |  Dweck, HKM. and Carlson, JR. 2020. Curr Biol. 30: 17-30.e3. PMID: 31839451
  9. Induction of CD4+CD25+ Regulatory T Cells from In Vitro Grown Human Mononuclear Cells by Sparteine Sulfate and Harpagoside.  |  Atwany, NZ., et al. 2020. Biology (Basel). 9: PMID: 32781652
  10. Effects of sparteine sulfate on glucagon secretion in insulin dependent (type-1) diabetic subjects.  |  Paolisso, G., et al. 1987. Horm Metab Res. 19: 389-90. PMID: 3311956
  11. Evolutionary shifts in taste coding in the fruit pest Drosophila suzukii.  |  Dweck, HK., et al. 2021. Elife. 10: PMID: 33616529
  12. Manganese and sparteine sulfate effects on mineral metabolism.  |  Howes, AD., et al. 1973. J Anim Sci. 37: 455-8. PMID: 4748478
  13. Mechanism of action of sparteine sulfate on myometrial activity in vitro.  |  Yamada, S., et al. 1968. Am J Obstet Gynecol. 101: 1089-95. PMID: 5663352
  14. Interaction of alkaloids with plant transfer ribonucleic acids. Effect of sparteine on lupin arginyl-tRNA formation.  |  Zwierzyński, T., et al. 1982. Chem Biol Interact. 42: 107-16. PMID: 6924863
  15. Effect of sparteine sulfate on uterine prostaglandin F in the rat.  |  Abtahi, FS., et al. 1978. Prostaglandins. 16: 473-82. PMID: 725080

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sparteine Sulfate, 250 mg

sc-471860
250 mg
$379.00