Sox-22 Antibody (86C2a): sc-81380

Sox-22 Antibody (86C2a) is a mouse monoclonal IgG2a antibody engineered to detect human Sox-22 protein with precision in western blotting (WB) and immunoprecipitation (IP) applications. Sox-22 monoclonal antibody (86C2a) is raised against a recombinant protein corresponding to an internal region of human Sox-22, ensuring robust and reliable binding to the target protein. Sox-22, also called SOX12, is a member of the SRY-related HMG-box (Sox) family of transcription factors, which are pivotal in regulating gene expression during embryonic development and cellular differentiation. Sox-22 functions as a transcriptional regulator, playing a crucial role in determining cell fate and orchestrating diverse developmental processes essential for proper tissue and organ formation. Sox-22′s involvement in these fundamental biological mechanisms underscores its importance in both normal physiological development and the pathology of various diseases. Dysregulation or mutations in Sox-22 have been linked to developmental disorders and conditions such as sex reversal, highlighting its significance in maintaining developmental integrity and its potential as a therapeutic target. Sox-22 (86C2a) antibody enables researchers to effectively investigate the expression patterns, functional roles, and regulatory mechanisms of Sox-22, thereby advancing our understanding of developmental biology and contributing to the identification of novel therapeutic strategies for related diseases.

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Sox-22 Antibody (86C2a) References:

1. Identification of a novel Sry-related gene and its germ cell-specific expression.  |  Osaki, E., et al. 1999. Nucleic Acids Res. 27: 2503-10. PMID: 10359848
2. Roles of Sox factors in neural determination: conserved signaling in evolution?  |  Sasai, Y. 2001. Int J Dev Biol. 45: 321-6. PMID: 11291862
3. Ancestry and diversity of the HMG box superfamily.  |  Laudet, V., et al. 1993. Nucleic Acids Res. 21: 2493-501. PMID: 8506143
4. Sox10, a novel transcriptional modulator in glial cells.  |  Kuhlbrodt, K., et al. 1998. J Neurosci. 18: 237-50. PMID: 9412504
5. Characterisation and mapping of the human SOX14 gene.  |  Arsic, N., et al. 1998. Cytogenet Cell Genet. 83: 139-46. PMID: 9925951

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Sox-22 Antibody (86C2a) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Sox-22 Antibody (86C2a) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Sox-22 Antibody (86C2a) Specifications

Alternate Product Name: SOX22

Product Clone Name: 86C2a

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Sox-22

Epitope Species: human

Product Reactivity/Detection: Sox-22

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Sox-22 Antibody (86C2a): N/A