Date published: 2025-10-3

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Sorbitan sesquioleate (CAS 8007-43-0)

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Alternate Names:
Arlacel® 83; Span® 83
Application:
Sorbitan sesquioleate is a nonionic surfactant
CAS Number:
8007-43-0
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sorbitan sesquioleate is a nonionic surfactant derived from the dehydration of sorbitol and primarily used in scientific studies related to surface chemistry and colloidal stability. In research, it serves as an emulsifying and dispersing agent, facilitating the formation and stabilization of emulsions and dispersions in a variety of experimental setups. This compound is particularly valuable for its ability to modify the surface properties of liquids, enhancing the miscibility of otherwise immiscible phases. Sorbitan sesquioleate′s role in research extends to studies on the kinetics of emulsion formation and the thermodynamic properties of colloids. By altering the interfacial tension between liquid phases, it provides insights into the molecular interactions that govern phase behavior and stability in colloidal systems. Researchers utilize this chemical to investigate the effects of surfactants on emulsion polymerization, drug delivery systems, and biochemical assays where precise control of the interface is required. The mechanism by which sorbitan sesquioleate operates—reducing surface tension and providing steric stabilization—makes it a crucial component in the formulation of stable emulsions and fine dispersions, contributing to advancements in both fundamental and applied surface chemistry.


Sorbitan sesquioleate (CAS 8007-43-0) References

  1. Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbitan isostearate, sorbitan olivate, sorbitan sesquiisostearate, sorbitan sesquistearate, and sorbitan triisostearate.  |  Lanigan, RS., et al. 2002. Int J Toxicol. 21 Suppl 1: 93-112. PMID: 12042063
  2. Sorbitan sesquioleate, a common emulsifier in topical corticosteroids, is an important contact allergen.  |  Asarch, A. and Scheinman, PL. 2008. Dermatitis. 19: 323-7. PMID: 19134436
  3. Sorbitan sesquioleate: an emerging contact allergen.  |  Asarch, A. and Scheinman, PL. 2008. Dermatitis. 19: 339-41. PMID: 19134439
  4. Reactivity to sorbitan sesquioleate affects reactivity to fragrance mix I.  |  Geier, J., et al. 2015. Contact Dermatitis. 73: 296-304. PMID: 26329727
  5. Sorbitan sesquioleate; a rare cause of contact allergy in consecutively patch tested dermatitis patients.  |  Bennike, NH. and Johansen, JD. 2016. Contact Dermatitis. 74: 242-5. PMID: 26806725
  6. Prevalence of Contact Allergens in Best-Selling Ophthalmic Products.  |  Om, A., et al. Dermatitis. 32: 273-279. PMID: 33400473
  7. Myroxylon pereirae (balsam of Peru): Still worth testing?  |  Guarneri, F., et al. 2021. Contact Dermatitis. 85: 269-273. PMID: 33748955
  8. Sorbitan sesquioleate: a rare contact allergen that is also an important indicator of allergic contact dermatitis from crossreacting compounds as well as for false-positive fragrance allergy.  |  Özkaya, E., et al. 2022. Clin Exp Dermatol. 47: 1291-1297. PMID: 35245949
  9. Use of sorbitan sesquioleate in patch test preparations and patch testing with the substance-What do our results mean?  |  Sukakul, T., et al. 2023. Contact Dermatitis. 88: 134-138. PMID: 36305668
  10. Testing with fragrance mix. Is the addition of sorbitan sesquioleate to the constituents useful?  |  Frosch, PJ., et al. 1995. Contact Dermatitis. 32: 266-72. PMID: 7634779

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sorbitan sesquioleate, 250 ml

sc-215896
250 ml
$51.00

Sorbitan sesquioleate, 1 L

sc-215896A
1 L
$162.00