Date published: 2025-10-31

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Sorbitan monostearate (CAS 1338-41-6)

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Application:
Sorbitan monostearate is An emulsifier. A nonionic surfactant.
CAS Number:
1338-41-6
Molecular Weight:
430.63
Molecular Formula:
C24H46O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sorbitan monostearate is a partial ester of stearic acid with sorbitol and its mono- and dianhydrides. Sorbitan monostearate, also referred to as Span 60TM or a synthetic wax, is an ester derived from sorbitan (a derivative of sorbitol) and stearic acid. Its main purpose is to serve as an emulsifier, ensuring the proper blending of water and oils.


Sorbitan monostearate (CAS 1338-41-6) References

  1. Sorbitan monostearate/polysorbate 20 organogels containing niosomes: a delivery vehicle for antigens?  |  Murdan, S., et al. 1999. Eur J Pharm Sci. 8: 177-86. PMID: 10379040
  2. Effect of sorbitan monostearate on the physical characteristics and whipping properties of whipped cream.  |  Zhao, Q., et al. 2013. Food Chem. 141: 1834-40. PMID: 23870898
  3. Development and characterization of sorbitan monostearate and sesame oil-based organogels for topical delivery of antimicrobials.  |  Singh, VK., et al. 2015. AAPS PharmSciTech. 16: 293-305. PMID: 25277240
  4. How Sorbitan Monostearate Can Increase Drug-Loading Capacity of Lipid-Core Polymeric Nanocapsules.  |  Poletto, FS., et al. 2015. J Nanosci Nanotechnol. 15: 827-37. PMID: 26328447
  5. A niosomal bilayer of sorbitan monostearate in complex with flavones: a molecular dynamics simulation study.  |  Myung, Y., et al. 2016. J Liposome Res. 26: 336-44. PMID: 26982006
  6. Delaying fat bloom formation in dark chocolate by adding sorbitan monostearate or cocoa butter stearin.  |  Buscato, MHM., et al. 2018. Food Chem. 256: 390-396. PMID: 29606464
  7. Potential role of resveratrol-loaded elastic sorbitan monostearate nanovesicles for the prevention of UV-induced skin damage.  |  Abbas, H. and Kamel, R. 2020. J Liposome Res. 30: 45-53. PMID: 30741053
  8. Cooling rate, sorbitan and glyceryl monostearate gelators elicit different microstructural, viscoelastic and textural properties in chia seed oleogels.  |  Trujillo-Ramírez, D., et al. 2019. Food Res Int. 119: 829-838. PMID: 30884722
  9. Effect of silicone oil on the microstructure, gelation and rheological properties of sorbitan monostearate-sesame oil oleogels.  |  Swe, MTH. and Asavapichayont, P. 2018. Asian J Pharm Sci. 13: 485-497. PMID: 32104422
  10. Re-evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives.  |  , ., et al. 2017. EFSA J. 15: e04788. PMID: 32625491
  11. Safety for the environment of sorbitan monolaurate as a feed additive for all animal species.  |  , ., et al. 2020. EFSA J. 18: e06162. PMID: 32874337
  12. Metformin hydrochloride entrapment in sorbitan monostearate for intestinal permeability enhancement and pharmacodynamics.  |  Mady, OY., et al. 2021. Sci Rep. 11: 20153. PMID: 34635740
  13. Fabrication of Stable Oleofoams with Sorbitan Ester Surfactants.  |  Liu, Y. and Binks, BP. 2022. Langmuir. 38: 14779-14788. PMID: 36410861

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sorbitan monostearate, 250 g

sc-281152
250 g
$42.00

Sorbitan monostearate, 1 kg

sc-281152A
1 kg
$88.00

Sorbitan monostearate, 5 kg

sc-281152B
5 kg
$300.00

Sorbitan monostearate, 10 kg

sc-281152C
10 kg
$500.00