Sorafenib-methyl-d3 (CAS 284461-73-0 (unlabeled))
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Sorafenib-methyl-d3 is a compound that functions as a kinase inhibitor, targeting multiple kinases involved in tumor cell proliferation and angiogenesis. It exerts its mechanism of action by inhibiting the activity of serine/threonine and receptor tyrosine kinases, including Raf kinases, VEGFR-2, VEGFR-3, PDGFR-β, Flt-3, and c-Kit. By doing so, it disrupts signaling pathways that are crucial for tumor growth and progression. This compound also has the ability to inhibit the Ras/Raf/MEK/ERK pathway, which is involved in cell proliferation and survival. It can block the VEGF signaling pathway, which plays a key role in angiogenesis. Sorafenib-methyl-d3′s mechanism of action involves targeting multiple kinases and signaling pathways that are dysregulated in cancer cells, thereby interfering with their growth and survival.
Sorafenib-methyl-d3 (CAS 284461-73-0 (unlabeled)) References
- Quantitation of terameprocol in human plasma by liquid chromatography-tandem mass spectrometry. | Anders, NM., et al. 2022. J Pharm Biomed Anal. 209: 114525. PMID: 34906921
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sorafenib-methyl-d3, 1 mg | sc-220126 | 1 mg | $305.00 |