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Solanesol (CAS 13190-97-1)

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Alternate Names:
(2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-Nonamethyl-2,6,10,14,18,22,26,30,34-hexa- triacontanonaen-1-ol
Application:
Solanesol is A high molecular weight isoprenoid alcohol
CAS Number:
13190-97-1
Molecular Weight:
631.07
Molecular Formula:
C45H74O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Solanesol is a long-chain polyisoprenoid alcohol that functions as a precursor in the biosynthesis of ubiquinone, also known as coenzyme Q. It plays a role in the mevalonate pathway, where it serves as a key intermediate in the synthesis of various isoprenoid compounds. Solanesol is involved in the formation of side chains of ubiquinone, which causes electrons to transport in the respiratory chain of cells. At the molecular level, solanesol interacts with enzymes and proteins involved in the biosynthesis of ubiquinone, facilitating the addition of isoprenoid units to the molecule. This interaction ultimately leads to the production of ubiquinone, which causes cellular respiration and energy production. Solanesol′s mechanism of action involves its incorporation into the structure of ubiquinone, contributing to the functionality of this important coenzyme.


Solanesol (CAS 13190-97-1) References

  1. Microwave-assisted extraction of solanesol from tobacco leaves.  |  Zhou, HY. and Liu, CZ. 2006. J Chromatogr A. 1129: 135-9. PMID: 16919654
  2. Recovery of solanesol from tobacco as a value-added byproduct for alternative applications.  |  Machado, PA., et al. 2010. Bioresour Technol. 101: 1091-6. PMID: 19773155
  3. A solanesol-derived scaffold for multimerization of bioactive peptides.  |  Alleti, R., et al. 2010. J Org Chem. 75: 5895-903. PMID: 20701315
  4. Solanesol: added value from Solanaceous waste.  |  Taylor, MA. and Fraser, PD. 2011. Phytochemistry. 72: 1323-7. PMID: 21459392
  5. Solanesol extraction from tobacco leaves by Flash chromatography based on molecularly imprinted polymers.  |  Ma, X., et al. 2016. J Chromatogr B Analyt Technol Biomed Life Sci. 1020: 1-5. PMID: 26994329
  6. Environmental and Genetic Factors Associated with Solanesol Accumulation in Potato Leaves.  |  Campbell, R., et al. 2016. Front Plant Sci. 7: 1263. PMID: 27610114
  7. Solanesol induces the expression of heme oxygenase-1 via p38 and Akt and suppresses the production of proinflammatory cytokines in RAW264.7 cells.  |  Yao, X., et al. 2017. Food Funct. 8: 132-141. PMID: 27921103
  8. Solanesol Biosynthesis in Plants.  |  Yan, N., et al. 2017. Molecules. 22: PMID: 28333111
  9. PEGylated Solanesol for Oral Delivery of Coenzyme Q10.  |  Qin, B., et al. 2017. J Agric Food Chem. 65: 3360-3367. PMID: 28418660
  10. mPEGylated solanesol micelles as redox-responsive nanocarriers with synergistic anticancer effect.  |  Qin, B., et al. 2017. Acta Biomater. 64: 211-222. PMID: 28963017
  11. A benign process for the recovery of solanesol from tomato leaf waste.  |  Arab, M., et al. 2019. Heliyon. 5: e01523. PMID: 31049434
  12. Bioactivities and Medicinal Value of Solanesol and Its Accumulation, Extraction Technology, and Determination Methods.  |  Yan, N., et al. 2019. Biomolecules. 9: PMID: 31382471
  13. Therapeutic carrier based on solanesol and hyaluronate for synergistic tumor treatment.  |  Zhang, M., et al. 2022. Int J Biol Macromol. 201: 20-28. PMID: 34998870

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Solanesol, 250 mg

sc-208398
250 mg
$29.00

Solanesol, 1 g

sc-208398A
1 g
$41.00

Solanesol, 5 g

sc-208398B
5 g
$83.00

Solanesol, 10 g

sc-208398C
10 g
$92.00

Solanesol, 25 g

sc-208398D
25 g
$246.00

Solanesol, 100 g

sc-208398E
100 g
$614.00

What is the degree of purity?

Asked by: Rampanellir
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate of Analysis on our website. Alternatively, please contact our Technical Service Department or reach out to your local distributor to inquire about the purity of our most recent lot.
Answered by: Technical Service
Date published: 2022-05-18
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Rated 5 out of 5 by from Yao et alYao et al. (PubMed ID 25645596) found that Solanesol pretected L02 cells from ethanol-induced damage via activation of HO-1 and Hsp70. -SCBT Publication Review
Date published: 2015-05-03
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Solanesol is rated 5.0 out of 5 by 1.
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