Molecular structure of Sodium Ursodeoxycholate, CAS Number: 2898-95-5
Sodium Ursodeoxycholate (CAS 2898-95-5)
Alternate Names:
Ursodeoxycholic Acid (sodium salt); UDCA
Application:
Sodium Ursodeoxycholate is NTCP inhibitor
CAS Number:
2898-95-5
Purity:
≥95%
Molecular Weight:
414.55
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sodium Ursodeoxycholate is a sodium taurocholate cotransporting polypeptide inhibitor. It may act to prevent the formation of reactive oxygen species and the translocation of Bax in liver cells. It is a sodium salt form of ursodeoxycholic acid, hydrated for stability and ease of handling. This compound is known for its involvement in the study of bile acid chemistry and its effects on biological systems.
Sodium Ursodeoxycholate (CAS 2898-95-5) References
- Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. | Kim, RB., et al. 1999. J Pharmacol Exp Ther. 291: 1204-9. PMID: 10565843
- Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study. | Jackson, H., et al. 2007. Hepatology. 46: 1131-7. PMID: 17685473
- Bile acids: regulation of apoptosis by ursodeoxycholic acid. | Amaral, JD., et al. 2009. J Lipid Res. 50: 1721-34. PMID: 19417220
- Ursodeoxycholic Acid Inhibits Inflammatory Responses and Promotes Functional Recovery After Spinal Cord Injury in Rats. | Ko, WK., et al. 2019. Mol Neurobiol. 56: 267-277. PMID: 29691718
- Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. | Craddock, AL., et al. 1998. Am J Physiol. 274: G157-69. PMID: 9458785
Inhibitor of:
Apoptosis.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sodium Ursodeoxycholate, 25 g | sc-296407 | 25 g | $333.00 |