Sodium Ursodeoxycholate CAS: 2898-95-5
MF: C24H39NaO4
MW: 414.55
NTCP inhibitor.
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Sodium Ursodeoxycholate (CAS 2898-95-5)

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Alternate Names: Ursodeoxycholic Acid (sodium salt); UDCA
Application: Sodium Ursodeoxycholate is NTCP inhibitor
CAS Number: 2898-95-5
Purity: ≥95%
Molecular Weight: 414.55
Molecular Formula: C24H39NaO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

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Sodium Ursodeoxycholate is a sodium taurocholate cotransporting polypeptide inhibitor. It has been shown to prevent the formation of reactive oxygen species and the translocation of Bax in liver cells.


References

1. Craddock, A.L. et al. 1998. Am. J. Physiol. 274(1 Pt 1): G157-G169. PMID: 9458785

2. Kim, R.B. et al. 1999. J. Pharmacol. Exp. Ther. 291(3): 1204-1209. PMID: 10565843

3. Jackson, H. et al. 2007. Hepatology. 46(4): 1131-1137. PMID: 17685473

4. Amaral, J.D. et al. 2009. J. Lipid Res. 50(9): 1721-1734. PMID: 19417220

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml) almost transparency.
Storage :
Store at room temperature
Boiling Point :
547.1° C at 760 mmHg
Optical Activity :
α20/D 48.5°±4.5°, c = 2 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD00065453

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Certificate of Analysis

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