Date published: 2025-9-22

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Sodium sulfite (CAS 7757-83-7)

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Alternate Names:
Disodium sulfite
Application:
Sodium sulfite is a pro-inflammatory compound that causes IL-8 production
CAS Number:
7757-83-7
Purity:
98%
Molecular Weight:
126.04
Molecular Formula:
Na2SO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium sulfite (Na2SO3) stands as a pivotal reagent in scientific research, boasting versatile properties and a wide range of applications across various disciplines. One of its primary mechanisms of action lies in its role as a reducing agent. Sodium sulfite′s ability to donate sulfur dioxide under acidic conditions makes it invaluable in research settings for the reduction of organic compounds and the stabilization of reactive intermediates. In organic synthesis, it facilitates the conversion of carbonyl compounds to their corresponding alcohols, and the reduction of nitro groups to amines. Additionally, sodium sulfite finds extensive use in analytical chemistry, particularly in the determination and quantification of certain analytes. Its reaction with iodine serves as a method for the titration of oxidizing agents and the determination of various substances, including iodometric and iodimetric titrations. Moreover, sodium sulfite is utilized in the paper and textile industries as a bleaching agent, where it effectively removes traces of residual chlorine from bleached products, preventing yellowing and improving color stability. Furthermore, research efforts have explored its potential in environmental science, where it is employed in water treatment processes to remove excess chlorine and as a reducing agent in the dechlorination of wastewater. Overall, sodium sulfite continues to be a versatile and indispensable tool in scientific investigations, owing to its diverse functionalities and broad utility in research applications spanning organic synthesis, analytical chemistry, industrial processes, and environmental science.


Sodium sulfite (CAS 7757-83-7) References

  1. Effect of sodium sulfite on mast cell degranulation and oxidant stress.  |  Collaco, CR., et al. 2006. Ann Allergy Asthma Immunol. 96: 550-6. PMID: 16680925
  2. Anti-candida activity of sodium sulfite.  |  Ogasawara, A., et al. 2008. Biol Pharm Bull. 31: 1101-3. PMID: 18520038
  3. Asthma drugs counter-regulate interleukin-8 release stimulated by sodium sulfite in an A549 cell line.  |  Yang, YF., et al. 2009. J Asthma. 46: 238-43. PMID: 19373630
  4. Sodium Sulfite-Involved Photocatalytic Radical Cascade Cyclization of 2-Isocyanoaryl Thioethers: Access to 2-CF2/CF3-Containing Benzothiazoles.  |  Yuan, Y., et al. 2019. Org Lett. 21: 469-472. PMID: 30588818
  5. Sodium Sulfite Exacerbates Allograft Vasculopathy and Affects Tryptophan Breakdown in Murine Heterotopic Aortic Transplantation.  |  Sucher, R., et al. 2019. Oxid Med Cell Longev. 2019: 8461048. PMID: 31089419
  6. Sodium sulfite causes gastric mucosal cell death by inducing oxidative stress.  |  Oshimo, M., et al. 2021. Free Radic Res. 55: 731-743. PMID: 34074194
  7. Sodium Sulfite-Induced Mast Cell Pyroptosis and Degranulation.  |  Liu, M., et al. 2021. J Agric Food Chem. 69: 7755-7764. PMID: 34191510
  8. Sodium Sulfite-Triggered Hepatocyte Ferroptosis via mtROS/Lysosomal Membrane Permeabilization-Mediated Lysosome Iron Efflux.  |  Liu, M., et al. 2023. J Agric Food Chem. 71: 16310-16322. PMID: 37871339
  9. Sodium sulfite triggered hepatic apoptosis, necroptosis, and pyroptosis by inducing mitochondrial damage in mice and AML-12 cells.  |  Liu, M., et al. 2024. J Hazard Mater. 467: 133719. PMID: 38335615
  10. Sodium Sulfite as a Novel Hypoxia Revulsant Involved in Hypoxic Regulation in Escherichia coli.  |  Ye, Q., et al. 2024. Biomed Environ Sci. 37: 228-232. PMID: 38582987

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium sulfite, 250 g

sc-203406
250 g
$30.00

Sodium sulfite, 2.5 kg

sc-203406A
2.5 kg
$100.00