sodium quinoline-8-thiolate (CAS 2801-16-3)

Sodium quinoline-8-thiolate, a sodium salt derived from quinoline-8-thiol, stands as a notable compound within the realm of chemical research, particularly for its unique electron-rich sulfur atom, which is directly bonded to the heterocyclic quinoline ring at the 8-position. This structural feature imparts significant nucleophilicity to the sulfur atom, enabling the compound to act as a potent ligand in coordination chemistry. Its ability to form stable complexes with various metal ions makes it useful in the synthesis of metal-organic frameworks (MOFs) and in the catalysis of reactions requiring precise metal ion environments. Moreover, the quinoline moiety of sodium quinoline-8-thiolate contributes aromatic stability and electronic properties that are exploited in photophysical studies and the development of fluorescent probes. The compound′s dual functionality, derived from its thiolate group and the quinoline ring, also facilitates its use in environmental chemistry for the detection and quantification of heavy metals, leveraging its selective binding properties to enable sensitive and selective sensing mechanisms.