Molecular structure of Sodium Pyruvate, CAS Number: 113-24-6
Sodium Pyruvate (CAS 113-24-6)
See product citations (14)
Alternate Names:
Pyruvic Acid Sodium Salt; α-Ketopropionic acid sodium salt; 2-Oxopropanoic acid sodium salt
Application:
Sodium pyruvate is an intermediate of sugar metabolism, an antioxidant, and an apoptosis inhibitor
CAS Number:
113-24-6
Molecular Weight:
110.04
Molecular Formula:
C3H3O3•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Sodium Pyruvate (Pyruvic Acid Sodium Salt) is an intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscles, pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion. It is a free radical scavenger and may act to protect against hydrogen peroxide mediated apoptosis.
Sodium Pyruvate (CAS 113-24-6) References
- Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. | Zhao, W., et al. 2000. Free Radic Res. 33: 23-30. PMID: 10826918
- Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death. | Miwa, H., et al. 2000. Free Radic Res. 33: 45-56. PMID: 10826920
- Pyruvate cycling and implications for regulation of gluconeogenesis in the insect, Manduca sexta L. | Thompson, SN. 2000. Biochem Biophys Res Commun. 274: 787-93. PMID: 10924355
- Effects of limited aeration and of the ArcAB system on intermediary pyruvate catabolism in Escherichia coli. | Alexeeva, S., et al. 2000. J Bacteriol. 182: 4934-40. PMID: 10940038
- [Effect of nutritional conditions on the fermentative production of pyruvic acid by Torulopsis glabrata]. | Li, Y., et al. 2000. Sheng Wu Gong Cheng Xue Bao. 16: 225-8. PMID: 10976333
- Role for mitochondrial oxidants as regulators of cellular metabolism. | Nemoto, S., et al. 2000. Mol Cell Biol. 20: 7311-8. PMID: 10982848
- New sequence data enable modelling of the fungal alternative oxidase and explain an absence of regulation by pyruvate. | Joseph-Horne, T., et al. 2000. FEBS Lett. 481: 141-6. PMID: 10996313
- Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock. | Slovin, PN., et al. 2001. Resuscitation. 50: 109-15. PMID: 11719137
- Sodium pyruvate protects against H(2)O(2) mediated apoptosis in human neuroblastoma cell line-SK-N-MC. | Jagtap, JC., et al. 2003. J Chem Neuroanat. 26: 109-18. PMID: 14599660
- Hypertonic sodium pyruvate solution is more effective than Ringer's ethyl pyruvate in the treatment of hemorrhagic shock. | Sharma, P. and Mongan, PD. 2010. Shock. 33: 532-40. PMID: 19953008
- Single sodium pyruvate ingestion modifies blood acid-base status and post-exercise lactate concentration in humans. | Olek, RA., et al. 2014. Nutrients. 6: 1981-92. PMID: 24841105
- Protective Effects of Sodium Pyruvate during Systemic Inflammation Limited to the Correction of Metabolic Acidosis. | Effenberger-Neidnicht, K., et al. 2019. Inflammation. 42: 598-605. PMID: 30357579
- Pyruvate affects inflammatory responses of macrophages during influenza A virus infection. | Abusalamah, H., et al. 2020. Virus Res. 286: 198088. PMID: 32634445
- Sodium Pyruvate Nasal Spray Reduces the Severity of Nasal Inflammation and Congestion in Patients with Allergic Rhinitis. | Martin, A., et al. 2022. J Aerosol Med Pulm Drug Deliv. 35: 291-295. PMID: 35960504
- Pyruvate prevents the onset of the cachectic features and metabolic alterations in myotubes downregulating STAT3 signaling. | Mannelli, M., et al. 2022. FASEB J. 36: e22598. PMID: 36305891
Inhibitor of:
Apoptosis.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sodium Pyruvate, 5 g | sc-208397 | 5 g | $46.00 | |||
Sodium Pyruvate, 25 g | sc-208397A | 25 g | $66.00 | |||
| US: (Out of Stock: Availability April 1, 2026) | ||||||