Date published: 2025-9-27

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Sodium pyrophosphate tetrabasic (CAS 7722-88-5)

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Alternate Names:
Tetrasodium pyrophosphate; TSPP; Phosphotex
Application:
Sodium pyrophosphate tetrabasic is anhydrous form, pyrophosphate salt used in buffers
CAS Number:
7722-88-5
Purity:
≥95%
Molecular Weight:
265.90
Molecular Formula:
Na4P2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium pyrophosphate tetrabasic, referred to as TSPP, plays a critical role in laboratory applications, particularly as a buffering agent. Its buffering capabilities are essential for maintaining the pH stability of various solutions, which is in analytical procedures and experimental setups. The unique chemical properties of Sodium pyrophosphate tetrabasic, including its ability to complex with metal ions, make it invaluable in the preparation of specialized buffers, such as the EDTA-sodium pyrophosphate extraction buffer. This specific buffer is notably effective in the extraction and analysis of microcystins from soil samples, a group of toxins produced by cyanobacteria that pose significant environmental and public health risks.


Sodium pyrophosphate tetrabasic (CAS 7722-88-5) References

  1. Cations reduce antimicrobial efficacy of lysozyme-chelator combinations.  |  Boland, JS., et al. 2004. J Food Prot. 67: 285-94. PMID: 14968960
  2. Optimization of an effective extraction procedure for the analysis of microcystins in soils and lake sediments.  |  Chen, W., et al. 2006. Environ Pollut. 143: 241-6. PMID: 16413641
  3. Effect of tetrasodium pyrophosphate on the physicochemical properties of yogurt gels.  |  Ozcan, T., et al. 2008. J Dairy Sci. 91: 4492-500. PMID: 19038924
  4. Mutagenicity of octane and tetrasodium pyrophosphate in bacterial reverse mutation (Ames) test.  |  Kim, SJ., et al. 2010. J Toxicol Sci. 35: 555-62. PMID: 20686342
  5. In vitro evaluation of the erosive potential of orange juice modified by food additives in enamel and dentine.  |  Scaramucci, T., et al. 2011. J Dent. 39: 841-8. PMID: 21945448
  6. Characterization of an acute muscle contraction model using cultured C2C12 myotubes.  |  Manabe, Y., et al. 2012. PLoS One. 7: e52592. PMID: 23300713
  7. Role of PCSK9 and IDOL in the pathogenesis of acquired LDL receptor deficiency and hypercholesterolemia in nephrotic syndrome.  |  Liu, S. and Vaziri, ND. 2014. Nephrol Dial Transplant. 29: 538-43. PMID: 24166456
  8. Redox proteins are constitutively secreted by skeletal muscle.  |  Manabe, Y., et al. 2014. J Physiol Sci. 64: 401-9. PMID: 25205643
  9. Anti-erosive properties of solutions containing fluoride and different film-forming agents.  |  Scaramucci, T., et al. 2015. J Dent. 43: 458-65. PMID: 25625672
  10. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells.  |  Ku, JM., et al. 2015. Mol Cell Biochem. 409: 33-43. PMID: 26169986
  11. Rap1 is Involved in Angiopoietin-1-Induced Cell-Cell Junction Stabilization and Endothelial Cell Sprouting.  |  Gaonac'h-Lovejoy, V., et al. 2020. Cells. 9: PMID: 31936361
  12. Detachment Procedure of Bacteria from Atmospheric Particles for Flow-cytometry Counting.  |  Araya, CM., et al. 2019. Bio Protoc. 9: e3273. PMID: 33654791
  13. Characterization of AgNPs and AuNPs in sewage sludge by single particle inductively coupled plasma-mass spectrometry.  |  Moreno-Martín, G., et al. 2022. Talanta. 238: 123033. PMID: 34857351
  14. Amidophosphoribosyltransferase (chicken liver).  |  Lewis, JM. and Hartman, SC. 1978. Methods Enzymol. 51: 171-8. PMID: 692384
  15. Tryptophanyl-tRNA synthetase from beef pancreas.  |  Kisselev, LL., et al. 1979. Methods Enzymol. 59: 234-57. PMID: 86935

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium pyrophosphate tetrabasic, 500 g

sc-236921
500 g
$61.00