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Sodium phytate (CAS 14306-25-3)

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Alternate Names:
Phytic Acid Dodecasodium Salt
Application:
Sodium phytate is a major phosphorus compound in plants that chelates with a variety of di- and trivalent cations
CAS Number:
14306-25-3
Purity:
≥95%
Molecular Weight:
923.8
Molecular Formula:
C6H6O24P612Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium phytate, also referred to as myo-inositol hexaphosphate, is a naturally occurring compound abundantly found in plants, grains, and legumes. Its unique structure comprises an inositol backbone with six phosphate groups attached, rendering it highly versatile for applications across the food, pharmaceutical, and cosmetic industries. Notably, sodium phytate serves as an antioxidant, preservative, and emulsifier. The precise mechanism underlying the effects of sodium phytate remains partially understood. However, current understanding suggests its involvement in chelating dietary minerals, impeding cholesterol and bile acid absorption, and scavenging free radicals. Additionally, sodium phytate is thought to interact with cell surface receptors and modulate the activity of diverse enzymes. Consequently, it elicits a broad spectrum of biochemical and physiological responses. Studies have demonstrated that sodium phytate can hinder the absorption of essential dietary minerals like calcium, iron, and zinc. Moreover, it can diminish cholesterol and bile acid absorption within the intestines. Beyond these effects, sodium phytate exhibits anti-inflammatory properties in vitro and holds potential in reducing the risk of cardiovascular disease.


Sodium phytate (CAS 14306-25-3) References

  1. Effect of dietary sodium phytate and microbial phytase on the lipase activity and lipid metabolism of broiler chickens.  |  Liu, N., et al. 2010. Br J Nutr. 103: 862-8. PMID: 20003570
  2. Effect of sodium phytate, sodium pyrophosphate and sodium tripolyphosphate on physico-chemical characteristics of restructured beef.  |  Lee, BJ., et al. 1998. Meat Sci. 50: 273-83. PMID: 22061146
  3. Dual effects of sodium phytate on the structural stability and solubility of proteins.  |  Bye, JW., et al. 2013. J Agric Food Chem. 61: 290-5. PMID: 23252762
  4. Development of chitosan-sodium phytate nanoparticles as a potent antibacterial agent.  |  Yang, J., et al. 2017. Carbohydr Polym. 178: 311-321. PMID: 29050599
  5. Chitosan-Sodium Phytate Films with a Strong Water Barrier and Antimicrobial Properties Produced via One-Step-Consecutive-Stripping and Layer-by-Layer-Casting Technologies.  |  Yang, J., et al. 2018. J Agric Food Chem. 66: 6104-6115. PMID: 29856622
  6. pH-Sensitive Chitosan-Sodium Phytate Core-Shell Hollow Beads and Nanocapsules for the Encapsulation of Active Ingredients.  |  Yang, J., et al. 2019. J Agric Food Chem. 67: 2894-2905. PMID: 30789724
  7. Enhanced viability of layer-by-layer encapsulated Lactobacillus pentosus using chitosan and sodium phytate.  |  Wang, M., et al. 2019. Food Chem. 285: 260-265. PMID: 30797343
  8. Preparation and characterisation of carboxymethyl-chitosan/sodium phytate composite membranes for adsorption in transformer oil.  |  Zheng, K., et al. 2019. Int J Biol Macromol. 132: 658-665. PMID: 30946908
  9. Effect of chitosan coatings incorporated sodium phytate on the shelf-life of Antarctic krill (Euphausia superba).  |  Liu, B. and Pan, S. 2020. Int J Biol Macromol. 151: 62-65. PMID: 32068063
  10. Exploring the Functional Properties of Sodium Phytate Doped Polyaniline Nanofibers Modified FTO Electrodes for High-Performance Binder Free Symmetric Supercapacitors.  |  Ur Rahman, S., et al. 2021. Polymers (Basel). 13: PMID: 34301084
  11. Qualitative and quantitative investigation on adsorption mechanisms of Cd(II) on modified biochar derived from co-pyrolysis of straw and sodium phytate.  |  Sun, D., et al. 2022. Sci Total Environ. 829: 154599. PMID: 35306071
  12. Effects of Enzymatic Modification and Cross-Linking with Sodium Phytate on the Structure and Physicochemical Properties of Cyperus esculentus Starch.  |  Wang, J., et al. 2022. Foods. 11: PMID: 36076768

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium phytate, 25 g

sc-203329
25 g
$120.00

Hello! I have a question about this product: is there any information on phosphorus content in it? Is it suitable for a phytase activity determination (as an enzyme substrate)? Thank you! Kind regards, Alexander Fedorov.

Asked by: faleks
Thank you for your question. Based on testing, the phosphorus content is 19.8%. Unfortunately we have no knowledge regarding suitability for phytase activity determination.
Answered by: Tech Service
Date published: 2019-03-22
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Rated 5 out of 5 by from FuFu, Q. et al. (PubMed 26385515) reported that Phytic acid can decrease the integrity of Caco-2 cell monolayers by modulating the tight junction (TJ) proteins' localization and down-regulating the expression of TJ proteins including claudin-1, occludin, and ZO-1. -SCBT Publication Review
Date published: 2015-04-12
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Sodium phytate is rated 5.0 out of 5 by 1.
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