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Sodium phosphate monobasic dihydrate (CAS 13472-35-0)

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Alternate Names:
Sodium dihydrogen phosphate dihydrate; Monosodium phosphate dihydrate
Application:
Sodium phosphate monobasic dihydrate is a high buffering capacity reagent
CAS Number:
13472-35-0
Molecular Weight:
156.01
Molecular Formula:
NaH2PO42H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium phosphate monobasic dihydrate serves as a pivotal reagent in various biochemical and preparative processes. This compound is particularly valued for its role in buffering solutions, where it helps maintain a stable pH by acting as a source of both phosphate ions and protons. In research applications, sodium phosphate monobasic dihydrate is frequently employed in the preparation of buffer solutions used in molecular biology, biochemistry, and chromatography. Its ability to establish a controlled environment is for enzyme reactions, nucleic acid experiments, and protein purification protocols. The compound′s utility extends to its participation in the synthesis of other phosphate compounds and in analytical chemistry, where it serves as a standard for calibrating equipment and as a reactant in specific assays. The dihydrate form, with two molecules of water per formula unit, ensures enhanced stability and solubility, making it a preferred choice for precise scientific applications.


Sodium phosphate monobasic dihydrate (CAS 13472-35-0) References

  1. Protein denaturation during freezing and thawing in phosphate buffer systems: monomeric and tetrameric beta-galactosidase.  |  Pikal-Cleland, KA., et al. 2000. Arch Biochem Biophys. 384: 398-406. PMID: 11368330
  2. Evaluation of capillary liquid chromatography-electrospray ionization ion mobility spectrometry with mass spectrometry detection.  |  Matz, LM., et al. 2002. J Chromatogr A. 946: 59-68. PMID: 11873983
  3. An allergic reaction to erythropoietin secondary to polysorbate hypersensitivity.  |  Limaye, S., et al. 2002. J Allergy Clin Immunol. 110: 530. PMID: 12209107
  4. Determination of tetracyclines in ovine milk by high-performance liquid chromatography with a coulometric electrode array system.  |  Zhao, F., et al. 2004. J Chromatogr A. 1055: 109-14. PMID: 15560486
  5. Rapid, two-step purification process for the preparation of pyrogen-free murine immunoglobulin G1 monoclonal antibodies.  |  Neidhardt, EA., et al. 1992. J Chromatogr. 590: 255-61. PMID: 1560097
  6. Hypersensitivity reactions to the polysorbate contained in recombinant erythropoietin and darbepoietin.  |  Steele, RH., et al. 2005. Nephrology (Carlton). 10: 317-20. PMID: 15958049
  7. Ion-pairing high-performance liquid chromatographic method for the determination of 5-aminosalicylic acid and related impurities in bulk chemical.  |  Kersten, BS., et al. 1991. J Chromatogr. 588: 187-93. PMID: 1818083
  8. Clarithromycin and Tetracycline Binding to Soil Humic Acid in the Absence and Presence of Calcium.  |  Christl, I., et al. 2016. Environ Sci Technol. 50: 9933-42. PMID: 27438991
  9. Determination of ochratoxin A in tissues of wild boar (Sus scrofa L.) by enzymatic digestion (ED) coupled to high-performance liquid chromatography with a fluorescence detector (HPLC-FLD).  |  Luci, G., et al. 2018. Mycotoxin Res. 34: 1-8. PMID: 28856595
  10. Characterisation of the site-specific monoPEGylated rhG-CSF analogue pegteograstim.  |  Hong, J., et al. 2018. Biologicals. 51: 54-61. PMID: 29107446
  11. NMR Spectroscopy-Based Metabolic Profiling of Biospecimens.  |  Sengupta, A. and Weljie, AM. 2019. Curr Protoc Protein Sci. 98: e98. PMID: 31763785
  12. Microdialysis and nanofiltration allow to distinguish molecularly dissolved from colloid-associated drug concentrations during biomimetic dissolution testing of supersaturating formulations.  |  Holzem, FL., et al. 2022. Eur J Pharm Sci. 174: 106166. PMID: 35283259
  13. Biopredictive capability assessment of two dissolution/permeation assays, µFLUX™ and PermeaLoop™, using supersaturating formulations of Posaconazole.  |  Holzem, FL., et al. 2022. Eur J Pharm Sci. 176: 106260. PMID: 35842141
  14. Pain perception following subcutaneous injections of citrate-buffered and phosphate-buffered epoetin alpha.  |  Yu, AW., et al. 1998. Int J Artif Organs. 21: 341-3. PMID: 9714028

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium phosphate monobasic dihydrate, 250 g

sc-251042
250 g
$40.00

Sodium phosphate monobasic dihydrate, 1 kg

sc-251042A
1 kg
$112.00

Sodium phosphate monobasic dihydrate, 5 kg

sc-251042B
5 kg
$316.00

About the sc-251042, i have a question Did it fulfill the NMPA?

Asked by: Peter123123123
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2024-07-23
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Rated 5 out of 5 by from Various publications cite the use of SodiumVarious publications cite the use of Sodium phosphate monobasic dihydrate in the preparation of biological buffers due to its very high buffering capacity. -SCBT Publication Review
Date published: 2015-05-09
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Sodium phosphate monobasic dihydrate is rated 5.0 out of 5 by 1.
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