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Sodium phosphate dibasic heptahydrate (CAS 7782-85-6)

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Application:
Sodium phosphate dibasic heptahydrate is A high buffering capacity reagent
CAS Number:
7782-85-6
Purity:
≥98%
Molecular Weight:
268.07
Molecular Formula:
Na2HPO47H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium phosphate dibasic heptahydrate, a compound with the chemical formula Na2HPO4•7H2O, serves as a vital reagent in scientific research, with its multifaceted properties finding diverse applications across various disciplines. One prominent mechanism of action involves its role as a buffering agent in biochemical and molecular biology experiments. Its ability to maintain pH stability in aqueous solutions makes it invaluable in the preparation of buffers for enzyme assays, nucleic acid hybridization studies, and cell culture media. Additionally, sodium phosphate dibasic heptahydrate is extensively utilized in the purification and crystallization of biological macromolecules, such as proteins and nucleic acids. Its capacity to form insoluble complexes with certain proteins aids in their isolation and purification, while its presence in crystallization solutions facilitates the growth of high-quality protein crystals suitable for X-ray crystallography and structural biology studies. Moreover, research efforts have explored its role as a component in the formulation of phosphate-based fertilizers, highlighting its significance in agricultural science and soil chemistry. Overall, sodium phosphate dibasic heptahydrate continues to be a cornerstone in scientific investigations, owing to its diverse functionalities and broad utility in research applications ranging from biochemistry and molecular biology to agricultural science and materials chemistry.


Sodium phosphate dibasic heptahydrate (CAS 7782-85-6) References

  1. Potassium and sodium chloride ion pairs are presumed to constitute a complex during elution from a Sephadex G-15 column with sodium phosphate buffer.  |  Okada, TK., et al. 2003. J Chromatogr A. 987: 49-55. PMID: 12613796
  2. High-Performance Liquid Chromatography Method for the Determination of Folic Acid in Fortified Food Products.  |  Lebiedzińska, A., et al. 2008. Toxicol Mech Methods. 18: 463-467. PMID: 19696945
  3. Meta-analysis: randomized controlled trials of 4-L polyethylene glycol and sodium phosphate solution as bowel preparation for colonoscopy.  |  Juluri, R., et al. 2010. Aliment Pharmacol Ther. 32: 171-81. PMID: 20384609
  4. Purification and assembly of human Argonaute, Dicer, and TRBP complexes.  |  De, N. and Macrae, IJ. 2011. Methods Mol Biol. 725: 107-19. PMID: 21528450
  5. Muscarinic cholinergic receptor mediated inhibitory transduction of adenylate cyclase activity in subcellular fractions from rat heart: improved detection in sodium phosphate buffer.  |  Jagadeesh, G., et al. 1990. Mol Cell Biochem. 93: 35-45. PMID: 2329994
  6. Decellularized Adipose Tissue Scaffolds for Soft Tissue Regeneration and Adipose-Derived Stem/Stromal Cell Delivery.  |  Morissette Martin, P., et al. 2018. Methods Mol Biol. 1773: 53-71. PMID: 29687381
  7. Electrostatic spray drying for monoclonal antibody formulation.  |  Mutukuri, TT., et al. 2021. Int J Pharm. 607: 120942. PMID: 34324986
  8. Influence of histone H1 on chromatin structure.  |  Thoma, F. and Koller, T. 1977. Cell. 12: 101-7. PMID: 561660
  9. Analytical methods for the quantification of free melamine and cyanuric acid in Nylon 6/6, 6 co‐polymer  |  Hamilton, D. W., & O'Neal, P. A. 2003. Journal of separation science. 26(6‐7): 510-514.
  10. Chiroptical Effect in Charge Transfer Processes in Chiral Carbon Dot-Doped Biopolymers: Application Toward Develo** Chiral Electrodes.  |  Burai, S., Waghmare, S., Chatterjee, A., Purkayastha, P., & Mondal, S. 2023. The Journal of Physical Chemistry C. 127(24): 11730-11735.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium phosphate dibasic heptahydrate, 100 g

sc-203402
100 g
$19.00

Sodium phosphate dibasic heptahydrate, 500 g

sc-203402A
500 g
$25.00

Sodium phosphate dibasic heptahydrate, 1 kg

sc-203402B
1 kg
$33.00

Sodium phosphate dibasic heptahydrate, 2.5 kg

sc-203402C
2.5 kg
$76.00

Sodium phosphate dibasic heptahydrate, 10 kg

sc-203402D
10 kg
$402.00

If you are making a buffering solution, could the anhydrous form be used and if so what would be the calculation to determine the amount compared to the heptahydrate?

Asked by: Phil10
The anhydrous form can be used as a component in the preparation of phosphate based buffers, but we do not have the amount you would need.
Answered by: Technical Support
Date published: 2018-12-11
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Rated 4 out of 5 by from SatisfiedClean label with simple and direct information. One thing that I really thought they missed was the molecular formula. The label is clean, but contains the "written name" of the chemical only, without the molecular formula. All procedures do not use the written name, but rather the molecular formula. So, it would be great if both written name and molecular formula were there!
Date published: 2021-03-18
Rated 5 out of 5 by from Various publications cite the use of SodiumVarious publications cite the use of Sodium phosphate dibasic heptahydrate for its very high buffering capacity. Useful in conjunction with Sodium Phopshate, Monobasic (sc-202342, sc-215883, or sc-251042) in the preparation of biological buffers. Has a wide range of applications including the purification of antibodies. -SCBT Publication Review
Date published: 2015-02-05
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Sodium phosphate dibasic heptahydrate is rated 4.5 out of 5 by 2.
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