Date published: 2025-9-14

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Sodium phosphate dibasic dihydrate (CAS 10028-24-7)

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Alternate Names:
Disodium hydrogen phosphate dihydrate
Application:
Sodium phosphate dibasic dihydrate is a reagent with high buffering capacity
CAS Number:
10028-24-7
Purity:
≥98%
Molecular Weight:
177.99
Molecular Formula:
Na2HPO42H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium phosphate dibasic dihydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic (sc-202342, sc-215883 or sc-251042) in the preparation of biological buffers. Used in many applications including the purification of antibodies. Additional forms available: Sodium Phosphate, Dibasic (sc-203277) Sodium phosphate dibasic heptahydrate (sc-203402) Sodium phosphate dibasic dodecahydrate (sc-236918) Sodium phosphate dibasic solution (sc-301828)


Sodium phosphate dibasic dihydrate (CAS 10028-24-7) References

  1. An allergic reaction to erythropoietin secondary to polysorbate hypersensitivity.  |  Limaye, S., et al. 2002. J Allergy Clin Immunol. 110: 530. PMID: 12209107
  2. Potassium and sodium chloride ion pairs are presumed to constitute a complex during elution from a Sephadex G-15 column with sodium phosphate buffer.  |  Okada, TK., et al. 2003. J Chromatogr A. 987: 49-55. PMID: 12613796
  3. Endogenous gamma-hydroxybutyric acid is in the rat, mouse and human gastrointestinal tract.  |  Tedeschi, L., et al. 2003. Life Sci. 72: 2481-8. PMID: 12650856
  4. Hypersensitivity reactions to the polysorbate contained in recombinant erythropoietin and darbepoietin.  |  Steele, RH., et al. 2005. Nephrology (Carlton). 10: 317-20. PMID: 15958049
  5. Nanoporous cerium oxide thin film for glucose biosensor.  |  Saha, S., et al. 2009. Biosens Bioelectron. 24: 2040-5. PMID: 19112013
  6. High-Performance Liquid Chromatography Method for the Determination of Folic Acid in Fortified Food Products.  |  Lebiedzińska, A., et al. 2008. Toxicol Mech Methods. 18: 463-467. PMID: 19696945
  7. Meta-analysis: randomized controlled trials of 4-L polyethylene glycol and sodium phosphate solution as bowel preparation for colonoscopy.  |  Juluri, R., et al. 2010. Aliment Pharmacol Ther. 32: 171-81. PMID: 20384609
  8. Muscarinic cholinergic receptor mediated inhibitory transduction of adenylate cyclase activity in subcellular fractions from rat heart: improved detection in sodium phosphate buffer.  |  Jagadeesh, G., et al. 1990. Mol Cell Biochem. 93: 35-45. PMID: 2329994
  9. ZnO-CuO composite matrix based reagentless biosensor for detection of total cholesterol.  |  Batra, N., et al. 2015. Biosens Bioelectron. 67: 263-71. PMID: 25168284
  10. Mineralized Hydrogels Induce Bone Regeneration in Critical Size Cranial Defects.  |  Wu, X., et al. 2021. Adv Healthc Mater. 10: e2001101. PMID: 32940013
  11. pH-Dependent supersaturation from amorphous solid dispersions of weakly basic drugs.  |  Wang, B., et al. 2022. Pharm Res. 39: 2919-2936. PMID: 34890018
  12. Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment.  |  Mastandrea, I., et al. 2022. STAR Protoc. 3: 101106. PMID: 35098162
  13. Modulation of Paracellular-like Drug Transport across an Artificial Biomimetic Barrier by Osmotic Stress-Induced Liposome Shrinking.  |  Eriksen, JB., et al. 2022. Pharmaceutics. 14: PMID: 35456555
  14. Highly Selective and Sensitive Voltammetric Method for the Detection of Catechol in Tea and Water Samples Using Poly(gibberellic acid)-Modified Carbon Paste Electrode.  |  Prinith, NS., et al. 2022. ACS Omega. 7: 24679-24687. PMID: 35874207
  15. Influence of histone H1 on chromatin structure.  |  Thoma, F. and Koller, T. 1977. Cell. 12: 101-7. PMID: 561660

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium phosphate dibasic dihydrate, 500 g

sc-236917B
500 g
$82.00

Sodium phosphate dibasic dihydrate, 1 kg

sc-236917
1 kg
$142.00

Sodium phosphate dibasic dihydrate, 2.5 kg

sc-236917A
2.5 kg
$234.00