Molecular structure of Sodium oleate, CAS Number: 143-19-1
Sodium oleate (CAS 143-19-1)
See product citations (3)
Alternate Names:
Oleic acid sodium salt
CAS Number:
143-19-1
Molecular Weight:
304.44
Molecular Formula:
C18H33O2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Sodium oleate, also known as oleic acid sodium, is a monounsaturated fatty acid abundant in human adipocytes and other tissues. It acts as an activator of Na+/K+ ATPase. Oleic acid stimulates cell proliferation and migration in highly metastatic cancer cells by enhancing β-oxidation through AMPK activation. Conversely, it inhibits cancer cell growth and survival in low metastatic carcinoma cells, including gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines. Furthermore, sodium oleate activates PKC (Protein Kinase C) in hepatocytes.
Sodium oleate (CAS 143-19-1) References
- Selective activation of phospholipase D2 by unsaturated fatty acid. | Kim, JH., et al. 1999. FEBS Lett. 454: 42-6. PMID: 10413092
- Cellular mechanism of sodium oleate-stimulated secretion of cholecystokinin and secretin. | Chang, CH., et al. 2000. Am J Physiol Gastrointest Liver Physiol. 279: G295-303. PMID: 10915637
- Enzymes in Ontogenesis: XVI. Activation of Protyrosinase by Sodium Alkyl Sulfates. | Allen, TH. and Bodine, JH. 1941. Proc Natl Acad Sci U S A. 27: 269-76. PMID: 16588457
- Oleic acid promotes changes in the subcellular distribution of protein kinase C in isolated hepatocytes. | Díaz-Guerra, MJ., et al. 1991. J Biol Chem. 266: 23568-76. PMID: 1748635
- Comparison of stages in oil agglomeration process of quartz with sodium oleate in the presence of Ca(II) and Mg(II) ions. | Ozkan, A., et al. 2009. J Colloid Interface Sci. 329: 81-8. PMID: 18849046
- Inhibition of gastric emptying by sodium oleate depends on length of intestine exposed to nutrient. | Lin, HC., et al. 1990. Am J Physiol. 259: G1031-6. PMID: 2260658
- Sodium Oleate-Based Nanoemulsion Enhances Oral Absorption of Chrysin through Inhibition of UGT-Mediated Metabolism. | Dong, D., et al. 2017. Mol Pharm. 14: 2864-2874. PMID: 27983856
- Effect of Sodium Oleate on the Adsorption Morphology and Mechanism of Nanobubbles on the Mica Surface. | Xiao, W., et al. 2019. Langmuir. 35: 9239-9245. PMID: 31268336
- Lipid Accumulation and IL-6 Production in L02 Hepatocytes Induced by Sodium Oleate: Dose and Time Dependence. | Chen, C., et al. 2021. Biomed Environ Sci. 34: 998-1004. PMID: 34981723
- Physicochemical characterization of green sodium oleate-based formulations. Part 3. Molecular and collective dynamics in rodlike and wormlike micelles by proton nuclear magnetic resonance relaxation. | Calucci, L., et al. 2023. J Colloid Interface Sci. 636: 279-290. PMID: 36640549
- Effects of Interfacial Hydroxylation Microstructure on Quartz Flotation by Sodium Oleate. | Zhang, H., et al. 2023. Langmuir. 39: 2182-2191. PMID: 36716219
- Synaptosomal phospholipase D potential role in providing choline for acetylcholine synthesis. | Hattori, H. and Kanfer, JN. 1985. J Neurochem. 45: 1578-84. PMID: 4045465
- A method for demonstrating prophenoloxidase after electrophoresis. | Nellaiappan, K. and Vinayakam, A. 1993. Biotech Histochem. 68: 193-5. PMID: 7692984
Activator of:
GPR119, and PKC.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sodium oleate, 250 mg | sc-215879 | 250 mg | $45.00 | |||
Sodium oleate, 1 g | sc-215879A | 1 g | $100.00 |