Date published: 2025-10-31

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Sodium n-hexadecyl sulfate (CAS 1120-01-0)

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Alternate Names:
n-Hexadecyl sulfate sodium salt
CAS Number:
1120-01-0
Molecular Weight:
344.49
Molecular Formula:
C16H33NaO4S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium n-hexadecyl sulfate (SDS) is a widely utilized surfactant. This zwitterionic detergent serves as a versatile tool in biochemical, biophysical, and physiological studies. Its non-ionic properties make it an effective solubilizer for proteins and lipids, rendering it invaluable for various laboratory experiments. Beyond research applications, Sodium n-hexadecyl sulfate finds its utility in diverse industrial sectors, including detergents, personal care products, and food additives. It enables the solubilization of proteins, lipids, and other biological molecules, and plays a role in studying enzyme kinetics, protein folding, membrane transport, membrane-bound proteins, and lipid-protein interactions.


Sodium n-hexadecyl sulfate (CAS 1120-01-0) References

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  2. Combination of ionic self-assembly and hydrogen bonding as a tool for the synthesis of liquid-crystalline materials and organogelators from a simple building block.  |  Camerel, F. and Faul, CF. 2003. Chem Commun (Camb). 1958-9. PMID: 12932052
  3. Determination of alkylphenols and linear alkylbenzene sulfonates in sediments applying accelerated solvent extraction (ASE).  |  Kreisselmeier, A. and Dürbeck, HW. 1996. Anal Bioanal Chem. 354: 921-4. PMID: 15048417
  4. An alternative study of the skin irritant effect of an homologous series of surfactants.  |  Kotani, M., et al. 1994. Toxicol In Vitro. 8: 229-33. PMID: 20692910
  5. Determination of alcohol sulfates and alcohol ethoxysulfates in marine and river sediments using liquid chromatography-tandem mass spectrometry.  |  Fernández-Ramos, C., et al. 2013. Talanta. 115: 606-15. PMID: 24054639
  6. Sorption and desorption of alcohol sulfate surfactants in an agricultural soil.  |  Fernández-Ramos, C., et al. 2014. Environ Toxicol Chem. 33: 508-15. PMID: 24288239
  7. Environmental monitoring of alcohol sulfates and alcohol ethoxysulfates in marine sediments.  |  Fernández-Ramos, C., et al. 2014. Environ Sci Pollut Res Int. 21: 4286-96. PMID: 24306720
  8. Evaluation of the levels of alcohol sulfates and ethoxysulfates in marine sediments near wastewater discharge points along the coast of Tenerife Island.  |  Fernández-Ramos, C., et al. 2014. Mar Pollut Bull. 79: 107-13. PMID: 24398419
  9. Toxicity of nanoparticle surface coating agents: Structure-cytotoxicity relationship.  |  Zhang, Y., et al. 2016. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 34: 204-215. PMID: 27323213
  10. Sol-Gel Behavior of Hydroxypropyl Methylcellulose (HPMC) in Ionic Media Including Drug Release.  |  Joshi, SC. 2011. Materials (Basel). 4: 1861-1905. PMID: 28824113
  11. Chemically Induced Morphogenesis of P22 Virus-like Particles by the Surfactant Sodium Dodecyl Sulfate.  |  Selivanovitch, E., et al. 2019. Biomacromolecules. 20: 389-400. PMID: 30462501
  12. Hydrophobic Ion Pairing of Small Molecules: How to Minimize Premature Drug Release from SEDDS and Reach the Absorption Membrane in Intact Form.  |  Spleis, H., et al. 2023. ACS Biomater Sci Eng. 9: 1450-1459. PMID: 36786693

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium n-hexadecyl sulfate, 1 g

sc-272490
1 g
$153.00

Sodium n-hexadecyl sulfate, 25 g

sc-272490A
25 g
$1846.00