Molecular structure of Sodium metavanadate, CAS Number: 13718-26-8
Sodium metavanadate (CAS 13718-26-8)
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Alternate Names:
Sodium (meta)vanadate; Sodium trioxovanadate; Sodium vanadate(V)
Application:
Sodium metavanadate is a useful hygroscopic compound
CAS Number:
13718-26-8
Purity:
≥98%
Molecular Weight:
121.93
Molecular Formula:
Na•O3V
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sodium metavanadate is a chemical compound that functions as an inhibitor of various enzymes, particularly those involved in the process of phosphorylation. It acts by interfering with the activity of protein tyrosine phosphatases, leading to the accumulation of phosphorylated proteins within the cell. This accumulation ultimately affects various cellular processes, including signal transduction, cell growth, and differentiation. Sodium metavanadate may act to modulate the activity of certain kinases, impacting their ability to phosphorylate target proteins. Sodium Metavanadate′s mechanism of action involves its interaction with specific amino acid residues within the active sites of enzymes, leading to the inhibition of their catalytic activity. Sodium metavanadate plays a role in modulating cellular signaling pathways and protein phosphorylation events.
Sodium metavanadate (CAS 13718-26-8) References
- Effects of sodium metavanadate on in vitro neuroblastoma and red blood cells. | Suwalsky, M., et al. 2013. Arch Biochem Biophys. 535: 248-56. PMID: 23608074
- Sodium metavanadate induced cognitive decline, behavioral impairments, oxidative stress and down regulation of myelin basic protein in mice hippocampus: Ameliorative roles of β-spinasterol, and stigmasterol. | Adebiyi, OE., et al. 2018. Brain Behav. 8: e01014. PMID: 29856129
- Intraperitoneal sodium metavanadate exposure induced severe clinicopathological alterations, hepato-renal toxicity and cytogenotoxicity in African giant rats (Cricetomys gambianus, Waterhouse, 1840). | Usende, IL., et al. 2018. Environ Sci Pollut Res Int. 25: 26383-26393. PMID: 29981023
- Oxidative stress changes observed in selected organs of African giant rats (Cricetomys gambianus) exposed to sodium metavanadate. | Usende, IL., et al. 2018. Int J Vet Sci Med. 6: 80-89. PMID: 30255083
- Biochemical and ultrastructural changes in kidney and liver of African Giant Rats (Cricetomysgambianus, Waterhouse, 1840) exposed to intraperitoneal sodium metavanadate (vanadium) intoxication. | Usende, IL., et al. 2020. Environ Toxicol Pharmacol. 79: 103414. PMID: 32442722
- Evaluation of the genotoxicity, cytotoxicity and antimalarial effect of sodium metavanadate po in a Plasmodium yoelii yoelii infected murine model. | Casarrubias-Tabarez, B., et al. 2020. Toxicol Rep. 7: 1001-1007. PMID: 32874923
- Sodium metavanadate treatment improves glycogen levels in multiple tissues in a model of metabolic syndrome caused by chronic cadmium exposure in Wistar rats. | Sarmiento-Ortega, VE., et al. 2021. Biometals. 34: 245-258. PMID: 33389338
- Anticancer effect of sodium metavanadate on murine breast cancer both in vitro and in vivo. | Tian, Y., et al. 2021. Biometals. 34: 557-571. PMID: 33689084
- Effects of Quercetin and Resveratrol on Zinc Chloride- and Sodium Metavanadate-Induced Passive Avoidance Memory Retention Deficits in Male Mice. | Hashemzaei, M., et al. 2021. Prev Nutr Food Sci. 26: 67-74. PMID: 33859961
- Reproductive Hormones Imbalance, Germ Cell Apoptosis, Abnormal Sperm Morphophenotypes and Ultrastructural Changes in Testis of African Giant Rats (Cricetomys gambianus) Exposed to Sodium Metavanadate Intoxication. | Usende, IL., et al. 2022. Environ Sci Pollut Res Int. 29: 42849-42861. PMID: 35088257
- Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water. | Waidyanatha, S., et al. 2022. Toxicol Lett. 360: 53-61. PMID: 35331842
- Corrigendum to 'Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water' [Toxicol. Lett. 360 (2022) 53-61]. | Waidyanatha, S., et al. 2023. Toxicol Lett. 373: 210. PMID: 36435680
- Bonding Heterogeneity Leads to Hierarchical and Ultralow Lattice Thermal Conductivity in Sodium Metavanadate. | Jin, X., et al. 2022. J Phys Chem Lett. 13: 11160-11168. PMID: 36442543
- Evaluation of immunotoxicity of sodium metavanadate following drinking water exposure in female B6C3F1/N mice in a 28-day study. | Frawley, R., et al. 2023. J Appl Toxicol.. PMID: 37403832
Inhibitor of:
ATP10A, ATP10B, ATP11A, ATP11B, ATP13A1, ATP13A3, ATP13A5, ATP8A1, CECR5, DNAH2, DNAH5, GLCE, GS1, HS3ST3A1, HS3ST6, MOCS3, PMCA4, PP2B-Aβ, PTP-H1, and STEAP.Activator of:
1700001O22Rik, ACP1, catalase, COX17, Dynein IC1, axonemal, FAM83E, FN3KRP, gp91-phox, MANEA, MoCo Sulfurase, Ndfip1, PP6, Rsk3, SUMF2, and V-ATPase A2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sodium metavanadate, 5 g | sc-251034 | 5 g | $32.00 | |||
Sodium metavanadate, 25 g | sc-251034A | 25 g | $84.00 |