Date published: 2025-12-30

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Sodium L-pyroglutamate (CAS 28874-51-3)

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CAS Number:
28874-51-3
Molecular Weight:
151.1
Molecular Formula:
C5H6NNaO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium L-pyroglutamate, often recognized for its role in the biochemical sector, serves as a pivotal sodium salt of the naturally occurring amino acid pyroglutamic acid (L-pyroglutamic acid). This compound is particularly esteemed for its ability to modulate various biochemical pathways, notably influencing cellular osmoregulation and acting as a mediator in neurotransmitter release processes. Its significance extends into research domains where it is utilized to study the intricate mechanisms of cellular signaling and neurophysiology. Sodium L-pyroglutamate′s capacity to affect glutamate levels, a critical neurotransmitter in the central nervous system, renders it useful in the exploration of neuronal function and plasticity. Furthermore, its involvement in protein solubility and stability examinations underscores its utility in the development of biochemical assays and in the enhancement of protein-based studies. Through its multifaceted roles, Sodium L-pyroglutamate contributes to a deeper understanding of cellular processes and the molecular underpinnings of neurobiology.


Sodium L-pyroglutamate (CAS 28874-51-3) References

  1. New polar constituents of the pupae of the silkworm Bombyx mori L. I. Isolation and identification of methionine sulfoxide, methionine sulfone, and gamma-cyclic di-L-glutamate.  |  Tanaka, R. 2007. Biosci Biotechnol Biochem. 71: 3055-62. PMID: 18071251
  2. Mechanism of extracellular ATP-induced depolarization in rat isolated ventricular cardiomyocytes.  |  Scamps, F. and Vassort, G. 1990. Pflugers Arch. 417: 309-16. PMID: 2125717
  3. Intercalation of chiral molecules into layered metal-organic frameworks: a strategy to synthesize homochiral MOFs.  |  Wen, Y., et al. 2013. Chem Commun (Camb). 49: 10644-6. PMID: 24100525

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium L-pyroglutamate, 1 g

sc-481835
1 g
$245.00