Date published: 2025-10-2

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Sodium iodide (CAS 7681-82-5)

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Application:
Sodium iodide is a useful reactant in the Finkelstein reaction
CAS Number:
7681-82-5
Purity:
≥99%
Molecular Weight:
149.89
Molecular Formula:
NaI
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium iodide is extensively used in scientific research, primarily for its role as a source of iodide ions in various chemical reactions. In organic synthesis, sodium iodide is commonly employed in the iodination of aromatic compounds, facilitating the introduction of iodine into organic molecules through nucleophilic substitution reactions. This is particularly important for creating compounds with enhanced reactivity and for subsequent transformations in multi-step synthetic pathways. Additionally, sodium iodide serves as a catalyst in Finkelstein reactions, where it promotes the exchange of halides, especially in the conversion of alkyl chlorides to alkyl iodides. Its high solubility in polar solvents makes it ideal for these applications. In the field of analytical chemistry, sodium iodide finds application in the preparation of iodometric solutions used for titrations to quantify oxidizing agents. The chemical′s role extends into the realm of materials science, where it is investigated for use in photovoltaic cells and radiation detection devices due to its scintillation properties when exposed to radiation. This broad range of applications highlights sodium iodide′s versatility and essential function in advancing experimental techniques and understanding in chemistry and materials science.


Sodium iodide (CAS 7681-82-5) References

  1. Radical scavenging as the mechanism for stimulation of prostaglandin cyclooxygenase and depression of inflammation by lipoic acid and sodium iodide.  |  Egan, RW., et al. 1978. Prostaglandins. 16: 861-9. PMID: 107544
  2. The effect of orally administered sodium iodide and sodium iodate on blood sugar response to thiourea in rats.  |  McCREESH, AH. and MANN, DE. 1958. J Am Pharm Assoc Am Pharm Assoc. 47: 56-7. PMID: 13491513
  3. Iodide-induced chemokines and genes related to immunological function in cultured human thyroid follicles in the presence of thyrotropin.  |  Yamazaki, K., et al. 2010. Thyroid. 20: 67-76. PMID: 20025541
  4. Multi-group approximation, scattering and calibration coefficients, uncertainty estimates and detection limits of a NaI(Tl)-based gamma spectrometry set-up for low-level activity analysis.  |  Owono, AP. 2010. J Environ Radioact. 101: 692-9. PMID: 20471729
  5. Photocatalytic decarboxylative alkylations mediated by triphenylphosphine and sodium iodide.  |  Fu, MC., et al. 2019. Science. 363: 1429-1434. PMID: 30923218
  6. Efficacy of sodium iodide for prevention of respiratory disease in preweaned dairy calves.  |  Gamsjäger, L., et al. 2020. Am J Vet Res. 81: 673-680. PMID: 32700995
  7. Halogen Bonding Heteroditopic Materials for Cooperative Sodium Iodide Binding and Extraction.  |  Docker, A., et al. 2021. Chemistry. 27: 14600-14604. PMID: 34520586
  8. [Generation of response functions of a NaI detector by using an interpolation technic].  |  Tominaga, S. 1983. Radioisotopes. 32: 101-8. PMID: 6688137
  9. A simple model for the refractive index of sodium iodide aqueous solutions  |  Narrow, T. L., Yoda, M., & Abdel-Khalik, S. I. 2000. Experiments in fluids. 28(3): 282-283.
  10. On the refractive index of sodium iodide solutions for index matching in PIV  |  Bai, K., & Katz, J. 2014. Experiments in fluids. 55: 1-6.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium iodide, 100 g

sc-203388
100 g
$66.00

Sodium iodide, 500 g

sc-203388A
500 g
$147.00

Sodium iodide, 2.5 kg

sc-203388B
2.5 kg
$540.00