Date published: 2025-12-19

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Sodium iodate (CAS 7681-55-2)

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Alternate Names:
Iodic acid, sodium salt
CAS Number:
7681-55-2
Purity:
≥99%
Molecular Weight:
197.89
Molecular Formula:
NaIO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium iodate (NaIO3) is a white crystalline compound extensively utilized in various scientific and industrial fields. As an inorganic iodate salt, it serves as a vital precursor to numerous iodates and iodides. Sodium iodate possesses potent oxidizing properties and finds application in synthesizing iodine compounds, as well as in the formulation of dyes and pigments. In scientific applications, sodium iodate plays a role in the synthesis of iodinated compounds, including iodinated proteins and polymers. The precise mechanism of action of sodium iodate remains partially understood. It is believed that this compound functions as a potent oxidizing agent capable of oxidizing various substrates. Furthermore, it is thought to exhibit catalytic properties, potentially forming complexes with other molecules during certain chemical reactions.


Sodium iodate (CAS 7681-55-2) References

  1. Sodium Iodate Disrupted the Mitochondrial-Lysosomal Axis in Cultured Retinal Pigment Epithelial Cells.  |  Lin, YC., et al. 2018. J Ocul Pharmacol Ther. 34: 500-511. PMID: 30020815
  2. Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death.  |  Chan, CM., et al. 2019. J Biomed Sci. 26: 40. PMID: 31118030
  3. Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics.  |  Yu, B., et al. 2020. Nat Commun. 11: 2549. PMID: 32439975
  4. Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress.  |  Qu, S., et al. 2020. Oxid Med Cell Longev. 2020: 1740943. PMID: 32695253
  5. Targeting the Notch and TGF-β signaling pathways to prevent retinal fibrosis in vitro and in vivo.  |  Fan, J., et al. 2020. Theranostics. 10: 7956-7973. PMID: 32724452
  6. Sodium iodate induces ferroptosis in human retinal pigment epithelium ARPE-19 cells.  |  Liu, B., et al. 2021. Cell Death Dis. 12: 230. PMID: 33658488
  7. HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration.  |  Tang, Z., et al. 2021. Redox Biol. 43: 101971. PMID: 33895485
  8. Sodium Iodate-Induced Degeneration Results in Local Complement Changes and Inflammatory Processes in Murine Retina.  |  Enzbrenner, A., et al. 2021. Int J Mol Sci. 22: PMID: 34502128
  9. 5-Lipoxygenase Inhibition Protects Retinal Pigment Epithelium from Sodium Iodate-Induced Ferroptosis and Prevents Retinal Degeneration.  |  Lee, JJ., et al. 2022. Oxid Med Cell Longev. 2022: 1792894. PMID: 35251467
  10. Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG.  |  Koster, C., et al. 2022. Int J Mol Sci. 23: PMID: 35328338
  11. Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis.  |  Yang, M., et al. 2022. Cell Death Dis. 13: 468. PMID: 35585057
  12. (-)-Epicatechin Provides Neuroprotection in Sodium Iodate-Induced Retinal Degeneration.  |  Peng, M., et al. 2022. Front Med (Lausanne). 9: 879901. PMID: 35833100
  13. Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.  |  Ren, C., et al. 2022. Oxid Med Cell Longev. 2022: 5961123. PMID: 35898618
  14. Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.  |  Henning, Y., et al. 2022. Cell Death Dis. 13: 662. PMID: 35906211
  15. Sodium iodate-induced retina degeneration observed in non-separate sclerochoroid/retina pigment epithelium/retina whole mounts.  |  Kim, SY., et al. 2022. Ann Eye Sci. 7: PMID: 36046548

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium iodate, 100 g

sc-251029
100 g
$46.00

Sodium iodate, 500 g

sc-251029A
500 g
$185.00