Date published: 2026-5-24

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Sodium hexanoate (CAS 10051-44-2)

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Alternate Names:
Sodium caproate; Hexanoic acid sodium salt
CAS Number:
10051-44-2
Purity:
≥99%
Molecular Weight:
138.14
Molecular Formula:
C6H11O2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium hexanoate, a carboxylate compound, has been used as an absorption enhancer for molecules. It may act to be active against various wild-type bacterial strains including Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. With a hydroxyl group, sodium hexanoate can react with inorganic acids to yield sodium salts. The fatty acid chains within sodium hexanoate function as cationic surfactants, enabling them to bind with proteins and hydroxyl groups on cell surfaces. This interaction disrupts the lipid bilayer of the cell membrane, which lead to cell death by osmotic lysis.


Sodium hexanoate (CAS 10051-44-2) References

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  2. Pseudomonas putida KT2442 as a platform for the biosynthesis of polyhydroxyalkanoates with adjustable monomer contents and compositions.  |  Tripathi, L., et al. 2013. Bioresour Technol. 142: 225-31. PMID: 23743426
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  4. Effects of small ionic amphiphilic additives on reverse microemulsion morphology.  |  Hatzopoulos, MH., et al. 2014. J Colloid Interface Sci. 421: 56-63. PMID: 24594032
  5. Biosynthesis of poly(3-hydroxybutyrate) and its copolymers by Yangia sp. ND199 from different carbon sources.  |  Huu Phong, T., et al. 2016. Int J Biol Macromol. 84: 361-6. PMID: 26708435
  6. Self-assembly of cationic gemini surfactants, alkanediyl-bis-(dimethyldodecyl-ammonium bromide), in cyclohexane: effects of spacer length on their association into reverse lyotropic liquid crystalline or reverse vesicles.  |  Deng, S. and Zhao, J. 2018. Soft Matter. 14: 734-741. PMID: 29340416
  7. Deletion of 76 genes relevant to flagella and pili formation to facilitate polyhydroxyalkanoate production in Pseudomonas putida.  |  Wang, J., et al. 2018. Appl Microbiol Biotechnol. 102: 10523-10539. PMID: 30338358
  8. Strong enrichment of atmospherically relevant organic ions at the aqueous interface: the role of ion pairing and cooperative effects.  |  Ekholm, V., et al. 2018. Phys Chem Chem Phys. 20: 27185-27191. PMID: 30339167
  9. Maternal short and medium chain fatty acids supply during early pregnancy improves embryo survival through enhancing progesterone synthesis in rats.  |  Ye, Q., et al. 2019. J Nutr Biochem. 69: 98-107. PMID: 31063920
  10. In-a-syringe surfactant-assisted dispersive liquid-liquid microextraction of polycyclic aromatic hydrocarbons in supramolecular solvent from tea infusion.  |  Timofeeva, I., et al. 2021. Talanta. 224: 121888. PMID: 33379097
  11. The Production of Biodegradable Polymers-medium-chain-length Polyhydroxyalkanoates (mcl-PHA) in Pseudomonas putida for Biomedical Engineering Applications.  |  Ene, N., et al. 2022. Curr Pharm Biotechnol. 23: 1109-1117. PMID: 34375190
  12. Statistical optimization of P(3HB-co-3HHx) copolymers production by Cupriavidus necator PHB-4/pBBR_CnPro-phaCRp and its properties characterization.  |  Trakunjae, C., et al. 2023. Sci Rep. 13: 9005. PMID: 37268758
  13. Absence of Na+--H+ barrier function in mucosa of canine small bowel.  |  Kelly, DG. and Code, CF. 1978. Can J Physiol Pharmacol. 56: 617-23. PMID: 688085
  14. The effect of short-chain fatty acids on the susceptibility of human umbilical vein endothelial cells to human cytomegalovirus infection.  |  Wu, QH., et al. 1994. J Virol Methods. 47: 37-50. PMID: 8051232

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium hexanoate, 10 g

sc-215874
10 g
$61.00

Sodium hexanoate, 25 g

sc-215874A
25 g
$152.00