Date published: 2025-10-17

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Sodium heptafluorobutyrate (CAS 2218-54-4)

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Alternate Names:
Heptafluorobutyric acid sodium salt
CAS Number:
2218-54-4
Molecular Weight:
236.02
Molecular Formula:
C4F7NaO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium heptafluorobutyrate, known as HFBA, is an organofluorine compound in many scientific applications, including as a reagent for the synthesis of organic compounds, a catalyst for various reactions. It is used to create esters, amides, and amines and is a catalyst for the synthesis of peptides and peptidomimetics. Sodium heptafluorobutyrate is an anion that can act as a nucleophile and a Lewis acid. It can be used to analyze and determine the presence of proteins, carbohydrates, and lipids. Sodium heptafluorobutyrate can inhibit the activity of multiple enzymes, such as proteases, phosphatases, and kinases, as well as inhibit the growth of various bacteria and fungi.


Sodium heptafluorobutyrate (CAS 2218-54-4) References

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  3. Carboxylato complexes of zirconium(IV) II: Heptafluorobutyrato complexes  |  C.M. Stables, H. Sutcliffe. 1987. Journal of the Less Common Metals. 135: 247-256.
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  5. Self-assembly of sodium heptafluorobutyrate in aqueous solution  |  Alfredo González-Pérez, Juan M. Ruso, Gerardo Prieto, Félix Sarmiento. 2004. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 249: 41-44.
  6. Partial molar volumes and partial molar adiabatic compressibilities of a short chain perfluorosurfactant: Sodium heptafluorobutyrate in aqueous solutions at different temperatures  |  Elena Blanco, Juan M. Ruso, Gerardo Prieto, Félix Sarmiento. 2005. The Journal of Chemical Thermodynamics. 37: 1351-1355.
  7. Rate constants for aqueous-phase reactions of SO4− with C2F5C(O)O− and C3F7C(O)O− at 298 K  |  Shuzo Kutsuna, Hisao Hori. 2007. 39: 276-288.
  8. One step preparation of polyaniline micro/nanohierarchical structures with superhydrophobicity  |  Haosen Fan, Ning Zhao, Hao Wang, Xiaofeng Li, Jian Xu. 2012. Materials Letters. 78: 42-45.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium heptafluorobutyrate, 5 g

sc-264318
5 g
$20.00

Sodium heptafluorobutyrate, 25 g

sc-264318A
25 g
$61.00