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Sodium glyoxylate monohydrate (CAS 918149-31-2)

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Alternate Names:
Glyoxylic acid sodium salt monohydrate; Oxoethanoic acid sodium salt
CAS Number:
918149-31-2
Purity:
≥93%
Molecular Weight:
114.03
Molecular Formula:
C2HNaO3•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium glyoxylate monohydrate (NaGly), a salt form of glyoxylate which is related to glycolic acid, is found in various plants and utilized as an intermediate in synthesizing diverse compounds. This compound dissolves in water and is incorporated into the manufacture of food additives and industrial chemicals, among other applications. In scientific research, Sodium glyoxylate monohydrate is employed for many purposes, including as a substrate for enzyme studies, a buffer for examining acid-base reactions, and a reagent in nucleic acid research. It also functions as a chelating agent in metal-catalyzed reaction investigations. Beyond its role in probing protein and nucleic acid structures and functions, Sodium glyoxylate monohydrate is believed to interact with enzymes and DNA polymerase, potentially inhibiting their activities by interfering with their active sites, although the full scope of its action requires further clarification.


Sodium glyoxylate monohydrate (CAS 918149-31-2) References

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  2. Fluorometric determination of pyridoxamine by conversion to pyridoxal cyanide compound.  |  TOEPFER, EW., et al. 1961. Anal Biochem. 2: 463-9. PMID: 13921534
  3. Ureide Catabolism in Soybeans: III. Ureidoglycolate Amidohydrolase and Allantoate Amidohydrolase Are Activities of an Allantoate Degrading Enzyme Complex.  |  Winkler, RG., et al. 1988. Plant Physiol. 86: 1084-8. PMID: 16666035
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  5. Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1.  |  Kukreja, A., et al. 2019. Nucleic Acid Ther. 29: 104-113. PMID: 30676254
  6. Synthesis and breakdown of universal metabolic precursors promoted by iron.  |  Muchowska, KB., et al. 2019. Nature. 569: 104-107. PMID: 31043728
  7. High-performance liquid chromatographic determination of glyoxylic acid in urine.  |  Petrarulo, M., et al. 1988. J Chromatogr. 432: 37-46. PMID: 3220907
  8. Determination of Ureides Content in Plant Tissues.  |  Lescano, I. 2020. Bio Protoc. 10: e3642. PMID: 33659312
  9. Proteomic characterisation of polyethylene terephthalate and monomer degradation by Ideonella sakaiensis.  |  Poulsen, JS. and Nielsen, JL. 2023. J Proteomics. 279: 104888. PMID: 36965770
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  13. New insight into the pyruvate decarboxylase-catalysed formation of lactaldehyde from H–D exchange experiments: a 'water proof' active site  |  Lobell, M., & Crout, D. H. 1996. Journal of the Chemical Society, Perkin Transactions 1. (13): 1577-1581.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium glyoxylate monohydrate, 1 g

sc-251025
1 g
$133.00

Sodium glyoxylate monohydrate, 5 g

sc-251025A
5 g
$535.00