Molecular structure of Sodium dehydrocholate, CAS Number: 145-41-5
Sodium dehydrocholate (CAS 145-41-5)
Alternate Names:
3,7,12-Trioxo-5β-cholanic acid sodium salt
Application:
Sodium dehydrocholate is a compound used to study biliary excretion
CAS Number:
145-41-5
Purity:
≥98%
Molecular Weight:
424.51
Molecular Formula:
C24H33O5•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sodium dehydrocholate (SDHC) is a bile salt that finds extensive use in laboratory experiments, particularly in the realm of biochemical and physiological studies. The precise mechanism of action underlying Sodium dehydrocholate remains incompletely understood. Nonetheless, it is believed that Sodium dehydrocholate binds to cell membranes, initiating a cascade of biochemical reactions that result in alterations in cell physiology and metabolism. Furthermore, it is thought to interact with various cellular components, including proteins and nucleic acids, thereby influencing gene expression and cellular metabolism.
Sodium dehydrocholate (CAS 145-41-5) References
- Anaphylactoid reaction to sodium dehydrocholate. | COGGINS, RP., et al. 1953. N Engl J Med. 249: 154-5. PMID: 13063703
- [Effects of sodium dehydrocholate and sodium glycocholate on lipoproteinogram of the dog and chicken]. | BIZARD, G., et al. 1956. C R Seances Soc Biol Fil. 150: 388-92. PMID: 13343688
- Blood velocity in semirecumbent patients receiving ether, dehydrocholate sodium and thiopental sodium. | MCCARTHY, FM. and HUBBELL, AO. 1957. Anesth Analg. 36: 29-30. PMID: 13425031
- Circulation time: sodium dehydrocholate versus sodium succinate with a case report of a systemic allergic reaction to sodium dehydrocholate. | SCHOENFELD, MR. and MESSELOFF, CR. 1961. Clin Pharmacol Ther. 2: 815-8. PMID: 13909099
- Anaphylactoid reaction after sodium dehydrocholate (Decholin). | MARTINEZ-LOPEZ, JI., et al. 1962. South Med J. 55: 274. PMID: 14470519
- Aqueous sodium dehydrocholate-sodium deoxycholate mixtures at low concentration. | Fernández-Leyes, MD., et al. 2007. J Colloid Interface Sci. 314: 659-64. PMID: 17612553
- Effects of sodium taurocholate and sodium dehydrocholate on bile flow, lipid and bilirubin secretion in sheep. | Bobowiec, R., et al. 1990. Acta Physiol Pol. 41: 146-54. PMID: 2136309
- Dehydrocholic Acid Ameliorates Sodium Taurocholate-Induced Acute Biliary Pancreatitis in Mice. | Zhang, X., et al. 2020. Biol Pharm Bull. 43: 985-993. PMID: 32475920
- The protective effect of experimental subarachnoid haemorrhage on sodium dehydrocholate-induced blood-brain barrier disruption. | Davis, RP., et al. 1986. Acta Neurochir (Wien). 83: 138-43. PMID: 3812038
- Electroencephalographic consequences of sodium dehydrocholate-induced blood-brain barrier disruption: Part 1. Acute and chronic effects of intracarotid sodium dehydrocholate. | Zappulla, RA., et al. 1985. Neurosurgery. 16: 630-8. PMID: 4000434
- Electroencephalographic consequences of sodium dehydrocholate-induced blood-brain barrier disruption: Part 2. Generation and propagation of spike activity after the topical application of sodium dehydrocholate. | Zappulla, RA., et al. 1985. Neurosurgery. 16: 639-43. PMID: 4000435
- Sodium dehydrocholate circulation times in digital subtraction angiography. | Becker, GJ. and Holden, RW. 1983. AJR Am J Roentgenol. 140: 817-8. PMID: 6601397
- Intracarotid dehydrocholate infusion: a new method for prolonged reversible blood-brain barrier disruption. | Spigelman, MK., et al. 1983. Neurosurgery. 12: 606-12. PMID: 6877542
- Influence of dehydrocholate sodium on the biliary reabsorption of sulfobromophtalein sodium from the rat biliary tree after retrograde intrabilary injection. | Dammann, HG., et al. 1976. Klin Wochenschr. 54: 789-91. PMID: 957600
- Interaction of sodium dehydrocholate and sodium cholate with polyvinyl pyrrolidone in aqueous medium. | Dutta, P. and Moulik, SP. 1998. Indian J Biochem Biophys. 35: 1-10. PMID: 9699412
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sodium dehydrocholate, 50 g | sc-396729 | 50 g | $57.00 |