Date published: 2025-9-24

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Sodium bicarbonate (CAS 144-55-8)

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Alternate Names:
Sodium hydrogen carbonate
Application:
Sodium bicarbonate is a commonly used laboratory pH neutralizer that reacts with acids and bases
CAS Number:
144-55-8
Purity:
≥99%
Molecular Weight:
84.01
Molecular Formula:
NaHCO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium bicarbonate, commonly known as baking soda, is a white crystalline compound with the formula NaHCO3, widely used in scientific research due to its versatile properties. As a mild base, it is frequently employed to neutralize acids, making it pivotal for adjusting and maintaining the pH levels in chemical and biochemical experiments where precise pH conditions are crucial for maintaining enzyme activities and reaction stabilities. In synthetic chemistry, sodium bicarbonate is utilized to produce effervescent reactions in the creation of carbon dioxide gas, particularly in combination with acids like citric or tartaric acid, which finds applications in experimental setups requiring gas evolution. Additionally, its role extends to environmental sciences, particularly in flue gas treatments where it helps remove sulfur dioxide from industrial emissions, significantly reducing air pollution. In analytical chemistry, sodium bicarbonate is integral in formulating buffer solutions that ensure the constancy of pH during sensitive laboratory procedures. This broad applicability, combined with its non-toxic nature and ease of handling, also makes it an excellent educational tool for demonstrating fundamental chemical principles such as acid-base reactions and gas release, thereby enhancing its value in both practical and instructional scientific contexts.


Sodium bicarbonate (CAS 144-55-8) References

  1. Sodium bicarbonate for the treatment of lactic acidosis.  |  Forsythe, SM. and Schmidt, GA. 2000. Chest. 117: 260-7. PMID: 10631227
  2. Addition of sodium bicarbonate to lidocaine decreases the duration of peripheral nerve block in the rat.  |  Sinnott, CJ., et al. 2000. Anesthesiology. 93: 1045-52. PMID: 11020760
  3. Effect of sodium bicarbonate infusion on serum osmolality, electrolyte concentrations, and blood gas tensions in cats.  |  Chew, DJ., et al. 1991. Am J Vet Res. 52: 12-7. PMID: 1850584
  4. Sodium bicarbonate therapy in patients with metabolic acidosis.  |  Adeva-Andany, MM., et al. 2014. ScientificWorldJournal. 2014: 627673. PMID: 25405229
  5. Sodium bicarbonate: A review and its uses in dentistry.  |  Madeswaran, S. and Jayachandran, S. 2018. Indian J Dent Res. 29: 672-677. PMID: 30409952
  6. Effects of Sodium Bicarbonate Ingestion on Measures of Wingate Test Performance: A Meta-Analysis.  |  Grgic, J. 2022. J Am Nutr Assoc. 41: 1-10. PMID: 33314967
  7. Sodium Bicarbonate in Different Critically Ill Conditions: From Physiology to Clinical Practice.  |  Coppola, S., et al. 2021. Anesthesiology. 134: 774-783. PMID: 33721887
  8. International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance.  |  Grgic, J., et al. 2021. J Int Soc Sports Nutr. 18: 61. PMID: 34503527
  9. Effects of sodium bicarbonate supplementation on exercise performance: an umbrella review.  |  Grgic, J., et al. 2021. J Int Soc Sports Nutr. 18: 71. PMID: 34794476

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium bicarbonate, 25 g

sc-203271
25 g
$20.00

Sodium bicarbonate, 500 g

sc-203271A
500 g
$28.00

Sodium bicarbonate, 1 kg

sc-203271B
1 kg
$42.00

Sodium bicarbonate, 5 kg

sc-203271C
5 kg
$82.00

Sodium bicarbonate, 25 kg

sc-203271D
25 kg
$683.00