Date published: 2026-4-5

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Sodium benzoate (CAS 532-32-1)

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Alternate Names:
Benzoic acid sodium salt
Application:
Sodium benzoate is a benzene compound used as a synthetic reagent
CAS Number:
532-32-1
Purity:
≥99%
Molecular Weight:
144.10
Molecular Formula:
C7H5O2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium benzoate is a reagent used in the synthesis of benzene-based derivatives, specifically 5-pyrazolinone derivatives, and aminoflavones and trihydroxybenzoyl flavanoid analogs. Sodium benzoate, a used preservative and food additive in various food and beverage products, is an organic compound represented by the chemical formula C7H5NaO2. This white crystalline powder dissolves easily in water but imparts a bitter taste. The application of sodium benzoate is widespread, appearing in a diverse array of products such as soft drinks, jams, jellies, pickles, pharmaceuticals, and cosmetics. Over the years, it has served as an effective preservative and holds the designation of being generally recognized as safe (GRAS) by the United States Food and Drug Administration (FDA). Despite its prevalent use, the exact mechanism of action of sodium benzoate remains somewhat elusive. However, it is believed that its impact is achieved by hindering the activity of enzymes involved in metabolizing fatty acids and other molecules. Moreover, studies have demonstrated that sodium benzoate interferes with the functioning of specific proteins responsible for governing cell signaling pathways. Sodium benzoate stands as a versatile and safe preservative utilized in a wide range of products, its precise mode of action being an ongoing area of scientific inquiry.


Sodium benzoate (CAS 532-32-1) References

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  2. Sodium benzoate and potassium sorbate preservatives in Iranian doogh.  |  Zamani Mazdeh, F., et al. 2014. Food Addit Contam Part B Surveill. 7: 115-9. PMID: 24914596
  3. [The reaction of fear in alcoholism].  |  Górski, P. 1978. Pieleg Polozna. 6-8. PMID: 251317
  4. Stability of Extemporaneously Prepared Sodium Benzoate Oral Suspension.  |  Atkins, JR., et al. 2018. Int J Pharm Compd. 22: 326-328. PMID: 30021187
  5. Aspirin, sodium benzoate and sodium salicylate reverse resistance to colistin in Enterobacteriaceae and Pseudomonas aeruginosa.  |  Malla, CF., et al. 2020. J Antimicrob Chemother. 75: 3568-3575. PMID: 32989461
  6. Toxicological impact of sodium benzoate on inflammatory cytokines, oxidative stress and biochemical markers in male Wistar rats.  |  Khan, IS., et al. 2022. Drug Chem Toxicol. 45: 1345-1354. PMID: 33003957
  7. Colorimetric quantification of sodium benzoate in food by using d-amino acid oxidase and 2D metal organic framework nanosheets mediated cascade enzyme reactions.  |  Zhang, H., et al. 2022. Talanta. 237: 122906. PMID: 34736643
  8. Efficacy and safety of add-on sodium benzoate, a D-amino acid oxidase inhibitor, in treatment of schizophrenia: A systematic review and meta-analysis.  |  Seetharam, JC., et al. 2022. Asian J Psychiatr. 68: 102947. PMID: 34890931
  9. Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Improves Cognitive Functions in Mice after Controlled Cortical Impact Injury.  |  Rangasamy, SB., et al. 2021. Int J Mol Sci. 23: PMID: 35008615
  10. Sodium benzoate induces neurobehavioral deficits and brain oxido-inflammatory stress in male Wistar rats: Ameliorative role of ascorbic acid.  |  Asejeje, FO., et al. 2022. J Biochem Mol Toxicol. 36: e23010. PMID: 35187746
  11. Sodium Benzoate-Harmfulness and Potential Use in Therapies for Disorders Related to the Nervous System: A Review.  |  Walczak-Nowicka, ŁJ. and Herbet, M. 2022. Nutrients. 14: PMID: 35406109
  12. Sodium benzoate and sodium bisulfate as preservatives in apple juice and alternative sanitizers for washing cherry tomatoes.  |  Chen, H., et al. 2022. Int J Food Microbiol. 372: 109697. PMID: 35525087
  13. Toxicological and Teratogenic Effect of Various Food Additives: An Updated Review.  |  Sambu, S., et al. 2022. Biomed Res Int. 2022: 6829409. PMID: 35782077
  14. Sodium benzoate induced toxicities in albino male rats: mitigating effects of Ficus carica and Cymbopogon citratus leave extract.  |  Yassien, EE., et al. 2022. Environ Sci Pollut Res Int. 29: 90567-90579. PMID: 35871196
  15. Sodium benzoate attenuates 2,8-dihydroxyadenine nephropathy by inhibiting monocyte/macrophage TNF-α expression.  |  Oshima, Y., et al. 2023. Sci Rep. 13: 3331. PMID: 36849798

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium benzoate, 250 g

sc-251009
250 g
$21.00