Date published: 2025-10-6

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Sodium acetylide suspension (CAS 1066-26-8)

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Alternate Names:
Ethynyl sodium
CAS Number:
1066-26-8
Purity:
95% (Purity of contained acetylide)
Molecular Weight:
48.02
Molecular Formula:
C2HNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Sodium acetylide suspension is a chemical that functions as a strong base in experiments. It acts by deprotonating acidic hydrogens, leading to the formation of acetylide anions. These anions can undergo various reactions, such as nucleophilic addition to electrophiles, making it a versatile reagent in organic synthesis. Sodium acetylide suspension can participate in alkylation reactions, allowing for the introduction of alkyl groups into organic molecules. Its mode of action involves the interaction of the acetylide anion with different substrates, leading to the formation of new carbon-carbon or carbon-heteroatom bonds. Sodium acetylide suspension′s function in experimental applications is to facilitate the synthesis of complex organic molecules by participating in key steps of the reaction pathways.


Sodium acetylide suspension (CAS 1066-26-8) References

  1. Chain epimerization during propylene polymerization with metallocene catalysts: mechanistic studies using a doubly labeled propylene.  |  Yoder, JC. and Bercaw, JE. 2002. J Am Chem Soc. 124: 2548-55. PMID: 11890805
  2. Tetrakis(N,N'-dimethylbenzamidinato)diruthenium(III) compounds bearing axial chloro and alkynyl ligands: a new family of redox rich diruthenium compounds.  |  Xu, G., et al. 2002. Inorg Chem. 41: 3521-7. PMID: 12079473
  3. Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.  |  Shen, S., et al. 2019. J Med Chem. 62: 8557-8577. PMID: 31414801
  4. Syntheses and molecular structures of hexasilylbenzenes and disilylacetylenes  |  Ruedinger, C., Bissinger, P., Beruda, H., & Schmidbaur, H. 1992. Organometallics. 11(8): 2867-2873.
  5. First nucleophilic addition of acetylide to 1, 3-diketonate anions: reaction of 1-aryl-4, 4, 4-trifluorobutane-1, 3-diones with sodium acetylide  |  Usachev, B. I. 2011. Tetrahedron letters. 52(50): 6726-6728.
  6. Preparation of a mechanically interlocked polymer from a linear supramolecular polymer.  |  Zhang, Z., Sun, K., Jin, L., Xie, C., & Li, S. 2020. Organic Chemistry Frontiers. 7(12): 1453-1462.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium acetylide suspension, 100 g

sc-224287
100 g
$57.00
US: Only available in the US

Sodium acetylide suspension, 500 g

sc-224287A
500 g
$237.00
US: Only available in the US