Superoxide Dismutase 1/SOD1 Antibody (72B1): sc-58421
- Superoxide Dismutase 1/SOD1 Antibody (72B1) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µl
- raised against full length SOD-1 of human origin
- recommended for detection of SOD-1 of human origin by WB, IP and ELISA
- See Superoxide Dismutase 1/SOD1 (G-11): sc-17767 for Superoxide Dismutase 1/SOD1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Superoxide Dismutase 1/SOD1 Antibody (72B1). This work is in progress.
SOD-1 Antibody (72B1) is a mouse monoclonal IgG1 antibody that detects Cu-Zn superoxide dismutase-1 (SOD-1) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). SOD-1 is a crucial cytosolic enzyme that plays a vital role in protecting cells from oxidative stress by catalyzing the dismutation of superoxide radicals into hydrogen peroxide and molecular oxygen, thereby mitigating potential cellular damage. The importance of SOD-1′s function is underscored by its involvement in various neurodegenerative diseases; mutations in the SOD-1 gene have been linked to conditions such as amyotrophic lateral sclerosis (ALS), where the loss of enzymatic activity leads to increased oxidative stress and neuronal death. SOD-1 operates as a homodimer and requires the binding of copper and zinc ions for activity, highlighting the significance of metal ion homeostasis in maintaining protective functions. Anti-SOD-1 antibody (72B1) serves as an essential tool for researchers investigating the role of oxidative stress in disease mechanisms and the therapeutic potential of targeting SOD-1 in neurodegenerative disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Superoxide Dismutase 1/SOD1 Antibody (72B1) | sc-58421 | 100 µl | $322.00 |