SNX29 Antibody (4B12): sc-134432
- SNX29 Antibody (4B12) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant RUNDC2A protein of human origin
- recommended for detection of SNX29 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SNX29 Antibody (4B12). This work is in progress.
SNX29 Antibody (4B12) is a mouse monoclonal IgG1 antibody that detects SNX29 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SNX29, also known as RUNDC2A, is an 813 amino acid protein characterized by one PX (phox homology) domain and one RUN domain, which play crucial roles in cellular processes such as membrane trafficking and endosomal sorting. SNX29 functions in regulating intracellular transport mechanisms, essential for maintaining cellular homeostasis and responding to environmental changes. Dysregulation of these processes can lead to various diseases, including neurodegenerative disorders and cancer. SNX29 exists as two alternatively spliced isoforms, and SNX29 gene is located on human chromosome 16p. This chromosome harbors over 900 genes and is implicated in several genetic disorders, including giant axonal neuropathy and Crohn′s disease. The identification of SNX29 and SNX29 interactions within the sorting nexin family highlights potential as a biomarker for studying these conditions and understanding the underlying mechanisms of related pathologies.
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SNX29 Antibody (4B12) References:
- Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. | Børglum, AD., et al. 2014. Mol Psychiatry. 19: 325-33. PMID: 23358160
- Gene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells. | Zhu, L., et al. 2015. Med Oncol. 32: 426. PMID: 25502083
- Recurrent genomic rearrangements in primary testicular lymphoma. | Twa, DD., et al. 2015. J Pathol. 236: 136-41. PMID: 25712539
- Novel sex-dependent differentially methylated regions are demethylated in adult male mouse livers. | Ito, S., et al. 2015. Biochem Biophys Res Commun. 462: 332-8. PMID: 25960295
- Probabilistic natural mapping of gene-level tests for genome-wide association studies. | Bao, F., et al. 2018. Brief Bioinform. 19: 545-553. PMID: 28200018
- Circular RNA SNX29 Sponges miR-744 to Regulate Proliferation and Differentiation of Myoblasts by Activating the Wnt5a/Ca2+ Signaling Pathway. | Peng, S., et al. 2019. Mol Ther Nucleic Acids. 16: 481-493. PMID: 31051333
- Genome-wide association analysis of autism identified multiple loci that have been reported as strong signals for neuropsychiatric disorders. | Xia, L., et al. 2020. Autism Res. 13: 382-396. PMID: 31647196
- SNX29, a new susceptibility gene shared with major mental disorders in Han Chinese population. | Chen, JH., et al. 2021. World J Biol Psychiatry. 22: 526-534. PMID: 33143498
- Pan-cancer analysis of the prognostic and immunological role of SNX29: a potential target for survival and immunotherapy. | Xu, C., et al. 2023. BMC Med Genomics. 16: 34. PMID: 36829159
- Detection distribution of CNVs of SNX29 in three goat breeds and their associations with growth traits. | Wang, Q., et al. 2023. Front Vet Sci. 10: 1132833. PMID: 37706075
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNX29 Antibody (4B12) | sc-134432 | 100 µg/ml | $339.00 |