Molecular structure of SNC 80, CAS Number: 156727-74-1
SNC 80 (CAS 156727-74-1)
See product citations (1)
Alternate Names:
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide
Application:
SNC 80 is a highly selective and potent non-peptide δ-opioid receptor (DOR) agonist
CAS Number:
156727-74-1
Purity:
≥98%
Molecular Weight:
449.63
Molecular Formula:
C28H39N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
SNC 80 is a compound that acts as a selective agonist for the κ-opioid receptor. This receptor is a type of G protein-coupled receptor that is involved in the modulation of pain, mood, and stress responses. SNC 80 has been studied in the context of its interactions with the κ-opioid receptor.
SNC 80 (CAS 156727-74-1) References
- SNC 80, a delta-opioid agonist, elicits phase advances in hamster circadian activity rhythms. | Byku, M. and Gannon, RL. 2000. Neuroreport. 11: 1449-52. PMID: 10841355
- Selective depression of nociceptive responses of dorsal horn neurones by SNC 80 in a perfused hindquarter preparation of adult mouse. | Cao, CQ., et al. 2001. Neuroscience. 107: 329-38. PMID: 11731107
- Different regulation of human delta-opioid receptors by SNC-80 [(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and endogenous enkephalins. | Lecoq, I., et al. 2004. J Pharmacol Exp Ther. 310: 666-77. PMID: 15102931
- Brain delta2 opioid receptors mediate SNC-80-evoked hypothermia in rats. | Rawls, SM., et al. 2005. Brain Res. 1049: 61-9. PMID: 15936000
- Increased survival of tumor-bearing mice by the delta opioid SNC 80. | Gomez-Flores, R., et al. 2005. Anticancer Res. 25: 4563-7. PMID: 16334142
- Chemotaxis of human and rat leukocytes by the delta-selective non-peptidic opioid SNC 80. | Ordaz-Sánchez, I., et al. 2003. Rev Latinoam Microbiol. 45: 16-23. PMID: 17061517
- Stimulation of Δ opioid receptor and blockade of nociceptin/orphanin FQ receptor synergistically attenuate parkinsonism. | Mabrouk, OS., et al. 2014. J Neurosci. 34: 12953-62. PMID: 25253844
- Human delta opioid receptor: functional studies on stably transfected Chinese hamster ovary cells after acute and chronic treatment with the selective nonpeptidic agonist SNC-80. | Malatynska, E., et al. 1996. J Pharmacol Exp Ther. 278: 1083-9. PMID: 8819489
- Central effect of SNC 80, a selective and systemically active delta-opioid receptor agonist, on gastrointestinal propulsion in the mouse. | Broccardo, M., et al. 1998. Eur J Pharmacol. 342: 247-51. PMID: 9548393
- Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW373U86 and SNC 80: 1. Locomotion, rearing and stereotypies in intact rats. | Spina, L., et al. 1998. Behav Pharmacol. 9: 1-8. PMID: 9832942
- Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW373U86 and SNC 80: 2. Place-preference and brain microdialysis studies in rats. | Longoni, R., et al. 1998. Behav Pharmacol. 9: 9-14. PMID: 9832943
- Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW 373U86 and SNC 80: 3. Facilitation of D1 and D2 responses in unilaterally 6-hydroxydopamine-lesioned rats. | Pinna, A. and Di Chiara, G. 1998. Behav Pharmacol. 9: 15-21. PMID: 9832944
Activator of:
DOR, DOR-1, and Morphine.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNC 80, 5 mg | sc-203267 | 5 mg | $84.00 | |||
SNC 80, 25 mg | sc-203267A | 25 mg | $326.00 |