SMIM13 Antibody (E-6): sc-398401

SMIM13 Antibody (E-6) is a mouse monoclonal IgG2a kappa light chain antibody that detects SMIM13 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SMIM13 (E-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SMIM13, consisting of 91 amino acids, is encoded by a gene located on chromosome 6p24, which is notable for involvement in various genetic disorders and diseases. SMIM13 plays a crucial role in cellular processes, including regulation of erythropoiesis and maintenance of red blood cell integrity, making SMIM13 significant in understanding conditions related to anemia and other hematological disorders. Additionally, chromosome 6, which houses SMIM13, is implicated in several diseases, including early onset intestinal cancer and various genetic syndromes, highlighting the importance of studying SMIM13 in the context of human health. Deletion of specific regions on chromosome 6 has been linked to cancer susceptibility, while mutations in associated genes can lead to conditions such as porphyria cutanea tarda and Stickler syndrome. Using anti-SMIM13 antibody (E-6) in research can provide valuable insights into functional implications of SMIM13 and potential role in disease mechanisms.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

SMIM13 Antibody (E-6) References:

1. The DNA sequence and analysis of human chromosome 6.  |  Mungall, AJ., et al. 2003. Nature. 425: 805-11. PMID: 14574404
2. A stop codon mutation in COL11A2 induces exon skipping and leads to non-ocular Stickler syndrome.  |  Vuoristo, MM., et al. 2004. Am J Med Genet A. 130A: 160-4. PMID: 15372529
3. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.  |  McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
4. Iron overload syndromes and the liver.  |  Batts, KP. 2007. Mod Pathol. 20 Suppl 1: S31-9. PMID: 17486050
5. The HLA-A1-B8 haplotype hitchhiking with the hemochromatosis mutation: does it affect the phenotype?  |  Olsson, KS., et al. 2007. Eur J Haematol. 79: 429-34. PMID: 17924859
6. Modulation of parkin gene expression in noradrenergic neuronal cells.  |  Park, E., et al. 2007. Int J Dev Neurosci. 25: 491-7. PMID: 17976945
7. A disease state mutation unfolds the parkin ubiquitin-like domain.  |  Safadi, SS. and Shaw, GS. 2007. Biochemistry. 46: 14162-9. PMID: 18004887
8. Recurrent deletions at 6q in early age of onset non-HNPCC- and non-FAP-associated intestinal carcinomas. Evidence for a novel cancer susceptibility locus at 6q14-q22.  |  Bläker, H., et al. 2008. Genes Chromosomes Cancer. 47: 159-64. PMID: 18008368

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-SMIM13 Antibody (E-6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-SMIM13 Antibody (E-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

SMIM13 Antibody (E-6) Specifications

Alternate Product Name: SMIM13

Product Clone Name: E-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 64-91

Epitope Target: SMIM13

Epitope Species: human

Product Reactivity/Detection: SMIM13

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for SMIM13 Antibody (E-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin