Molecular structure of SM-21 maleate, CAS Number: 155058-71-2
SM-21 maleate (CAS 155058-71-2)
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Alternate Names:
(±)-Tropanyl 2-(4-chlorophenoxy)butanoate maleate
Application:
SM-21 maleate is potent and selective σ2 antagonist, increasing release of ACh
CAS Number:
155058-71-2
Purity:
≥98%
Molecular Weight:
453.92
Molecular Formula:
C18H24ClNO3•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
SM-21 maleate is a potent and selective σ receptor (σ2) antagonist with central effects following systemic administration. SM-21 maleate increases release of acetylcholine at central muscarinic synapses. SM-21 maleate is a potent analgesic (efficacy comparable to morphine) and nootropic agent.
SM-21 maleate (CAS 155058-71-2) References
Ghelardini et al (1997) Antinociceptive profile of 3-a-tropanyl-(2-Cl)-acid phenoxybutyrate (SM-21): a novel analgesic with a presynaptic cholinergic mechanism of action. J.Pharmacol.Exp.Ther. 282 430. Ghelardini et al (2000) Pharmacological identification of SM-21, the novel s2 antagonist. Pharmacol.Biochem.Behav. 67 659. Matsumoto and Mack (2001) (±)-SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice. Eur.J.Pharmacol. 417 R1.Inhibitor of:
Sigma Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SM-21 maleate, 10 mg | sc-204289 | 10 mg | $157.00 | |||
SM-21 maleate, 50 mg | sc-204289A | 50 mg | $651.00 |