SKF 83959 (CAS 67287-95-0)

SKF 83959 (CAS 67287-95-0) References

1. Sub-chronic administration of the dopamine D(1) antagonist SKF 83959 in bilaterally MPTP-treated rhesus monkeys: stable therapeutic effects and wearing-off dyskinesia.  |  Andringa, G., et al. 1999. Psychopharmacology (Berl). 146: 328-34. PMID: 10541734
2. Dissociation of cocaine-antagonist properties and motoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434.  |  Platt, DM., et al. 2000. J Pharmacol Exp Ther. 293: 1017-26. PMID: 10869406
3. Aberrant behavioral effects of a dopamine D1 receptor antagonist and agonist in monkeys: evidence of uncharted dopamine D1 receptor actions.  |  Peacock, L. and Gerlach, J. 2001. Biol Psychiatry. 50: 501-9. PMID: 11600103
4. SKF 83959 is an antagonist of dopamine D1-like receptors in the prefrontal cortex and nucleus accumbens: a key to its antiparkinsonian effect in animals?  |  Cools, AR., et al. 2002. Neuropharmacology. 42: 237-45. PMID: 11804620
5. Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines.  |  Neumeyer, JL., et al. 2003. Eur J Pharmacol. 474: 137-40. PMID: 12921854
6. The atypical dopamine D1 receptor agonist SKF 83959 induces striatal Fos expression in rats.  |  Wirtshafter, D. and Osborn, CV. 2005. Eur J Pharmacol. 528: 88-94. PMID: 16324697
7. Behavioral effects of the R-(+)- and S-(-)-enantiomers of the dopamine D(1)-like partial receptor agonist SKF 83959 in monkeys.  |  Desai, RI., et al. 2007. Eur J Pharmacol. 558: 98-106. PMID: 17207791
8. Assessment of jaw movements by magnetic sensor in relation to topographies of orofacial behaviour in freely moving rats: Studies with the dopamine D(1)-like receptor agonists SKF 83822 vs SKF 83959.  |  Fujita, S., et al. 2010. Eur J Pharmacol. 632: 39-44. PMID: 20122923
9. Orofacial movements in phospholipase C-related catalytically inactive protein-1/2 double knockout mice: Effect of the GABAergic agent diazepam and the D(1) dopamine receptor agonist SKF 83959.  |  Tomiyama, K., et al. 2010. Synapse. 64: 714-20. PMID: 20340178
10. SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C.  |  Lee, SM., et al. 2014. Neuropharmacology. 86: 145-54. PMID: 24929112
11. Dopamine D1 receptor signaling: does GαQ-phospholipase C actually play a role?  |  Lee, SM., et al. 2014. J Pharmacol Exp Ther. 351: 9-17. PMID: 25052835
12. Allosteric modulation of sigma-1 receptors elicits anti-seizure activities.  |  Guo, L., et al. 2015. Br J Pharmacol. 172: 4052-65. PMID: 25989224
13. Allosteric modulation of sigma-1 receptors by SKF83959 inhibits microglia-mediated inflammation.  |  Wu, Z., et al. 2015. J Neurochem. 134: 904-14. PMID: 26031312
14. The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction.  |  Perreault, ML., et al. 2017. Eur J Neurosci. 46: 2015-2025. PMID: 28677227
15. The alleged dopamine D1 receptor agonist SKF 83959 is a dopamine D1 receptor antagonist in primate cells and interacts with other receptors.  |  Andringa, G., et al. 1999. Eur J Pharmacol. 364: 33-41. PMID: 9920182