Molecular structure of (±)-SKF-38393 hydrochloride, CAS Number: 62717-42-4
(±)-SKF-38393 hydrochloride (CAS 62717-42-4)
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Alternate Names:
(±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride
Application:
(±)-SKF-38393 hydrochloride is A D1DR (D1 Dopamine receptor) agonist primarily as a research tool
CAS Number:
62717-42-4
Purity:
≥98%
Molecular Weight:
291.77
Molecular Formula:
C16H17NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(±)-SKF-38393 hydrochloride is a D1DR (D1 Dopamine receptor) agonist primarily as a research tool. SKF 38393 hydrochloride is a benzazepine compound known for its activity as a D1/D5 receptor partial agonist. With an IC50 value of 110 nM, it functions as a D1 agonist. The primary target of SKF 38393 is the dopamine D1 receptor (D1DR), and its agonism in vitro leads to induced desynchronization of electroencephalographic activity in rats. Moreover, SKF 38393 hydrochloride also exhibits agonistic behavior towards the serotonin SR-2C receptor (5-HT1C receptor). In addition to its D1/D5 receptor activation, it acts as an activator of the D5DR. Being a synthetic compound of the benzazepine chemical class, SKF 38393 displays stimulant and anorectic effects. Notably, it enhances the frequency of mEPSCs (miniature excitatory postsynaptic currents) in a concentration-dependent manner.
(±)-SKF-38393 hydrochloride (CAS 62717-42-4) References
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Activator of:
D1DR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)-SKF-38393 hydrochloride, 100 mg | sc-264306 | 100 mg | $179.00 | |||
(±)-SKF-38393 hydrochloride, 500 mg | sc-264306A | 500 mg | $707.00 |