SK-N-MC Cell Lysate: sc-2237
- 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
- human whole cell lysate; neuroepithelioma cells
- whole cell lysate provided as Western blotting positive control
- should be stored at -20°C and repeated freezing and thawing should be minimized
- sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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SK-N-MC cell lysate originates from a human neuroepithelioma cell line, primarily used to study neuronal differentiation and neuroepithelial tumor biology. This lysate is particularly valuable for investigating the signaling pathways and transcriptional networks involved in the differentiation processes of neuroepithelial cells. It provides a comprehensive resource for analyzing protein-protein interactions and for identifying biomarkers related to neuroepithelial cell functions and transformations. The use of SK-N-MC lysate in research has facilitated the exploration of intracellular dynamics, such as calcium signaling and neuronal receptor activity, which are crucial for understanding the behavior of neuroepithelial cells under various experimental conditions. Additionally, researchers utilize this lysate to study the effects of genetic modifications and chemical treatments on cell cycle regulation and apoptosis. This focus on basic cellular and molecular mechanisms makes SK-N-MC cell lysate an essential tool in cellular biology research, aiding in the elucidation of complex biological processes. Such studies contribute significantly to the foundational knowledge in neurobiology and cellular research fields.
SK-N-MC Cell Lysate References:
- Induction of electrical excitability by NGF requires autocrine action of a CNTF-like factor. | Lesser, SS., et al. 1999. Mol Cell Neurosci. 14: 169-79. PMID: 10576888
- Inhibitory effects of nitric oxide and nitrosative stress on dopamine-beta-hydroxylase. | Zhou, X., et al. 2000. J Biol Chem. 275: 21241-6. PMID: 10887204
- Receptor regulation of gene expression of axon guidance molecules: implications for adaptation. | Jassen, AK., et al. 2006. Mol Pharmacol. 70: 71-7. PMID: 16595738
- Inhibitory effects of pesticides on proteasome activity: implication in Parkinson′s disease. | Wang, XF., et al. 2006. Neurobiol Dis. 23: 198-205. PMID: 16626962
- AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release. | Bendor, J., et al. 2010. EMBO J. 29: 2813-26. PMID: 20664521
- Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells. | He, T. and Katusic, ZS. 2012. Microvasc Res. 83: 366-71. PMID: 22261313
- Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1. | Chavez-Valdez, R., et al. 2014. Neuroscience. 260: 106-19. PMID: 24361177
- RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2. | Li, PP., et al. 2021. Mov Disord. 36: 2519-2529. PMID: 34390268
- CD2 signalling induces phosphorylation of CREB in primary lymphocytes. | Guyot, DJ., et al. 1998. Immunology. 95: 544-52. PMID: 9893043
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SK-N-MC Cell Lysate | sc-2237 | 500 µg/200 µl | $118.00 |