SK-MEL-24 Whole Cell Lysate: sc-364259

SK-MEL-24 whole cell lysate is derived from a human melanoma cell line, frequently used to study melanoma biology under research contexts. This lysate provides a comprehensive profile of cellular components, enabling detailed analyses of protein expression, post-translational modifications, and interactions that occur within melanoma cells. Researchers utilize SK-MEL-24 lysate to explore the molecular basis of melanoma pathogenesis, focusing on signaling pathways such as BRAF, NRAS, and PI3K/Akt, which are often altered in melanoma. The lysate aids in examining the effects of genetic mutations endemic to melanoma, such as alterations in the BRAF gene, on the cellular phenotype and behavior. This includes studying the regulatory mechanisms of cell proliferation, apoptosis, and senescence. Additionally, SK-MEL-24 lysate is crucial for understanding melanoma's metabolic adaptations, providing insights into how these cells modulate their metabolism to support rapid growth and survival. The use of this lysate in basic scientific research allows for a deeper comprehension of the intrinsic properties of melanoma cells, contributing significantly to the foundational knowledge of cellular and molecular mechanisms.