Sisomicin sulfate salt (CAS 53179-09-2)
QUICK LINKS
Sisomicin sulfate salt is a compound of interest within the field of microbiology, particularly in the study of aminoglycoside antibiotics and their interactions with bacterial pathogens. It is used as a reference molecule in research aimed at understanding the mechanisms of action of aminoglycosides, which involve binding to the bacterial ribosome and disrupting protein synthesis. The sulfate salt form of sisomicin provides increased solubility for in vitro experiments, facilitating its use in assays and studies. Research involving sisomicin sulfate salt also encompasses investigations into bacterial resistance mechanisms, as understanding how bacteria develop resistance to aminoglycosides can inform the development of new strategies to combat antimicrobial resistance.
Sisomicin sulfate salt (CAS 53179-09-2) References
- Changes in the antibacterial activity of melanin-bound drugs. | Fukuda, M. and Sasaki, K. 1990. Ophthalmic Res. 22: 123-7. PMID: 2111531
- DNA-aptamers binding aminoglycoside antibiotics. | Nikolaus, N. and Strehlitz, B. 2014. Sensors (Basel). 14: 3737-55. PMID: 24566637
- Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography. | Wlasichuk, KB., et al. 2015. J Pharm Biomed Anal. 111: 126-30. PMID: 25880243
- Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography-tandem mass spectrometry. | Díez, C., et al. 2015. Anal Chim Acta. 882: 127-39. PMID: 26043099
- Polymyxin B and polymyxin E induce anaphylactoid response through mediation of Mas-related G protein-coupled receptor X2. | Zhan, Y., et al. 2019. Chem Biol Interact. 308: 304-311. PMID: 31132327
- Manufacture of pH- and HAase-responsive hydrogels with on-demand and continuous antibacterial activity for full-thickness wound healing. | Guan, S., et al. 2020. Int J Biol Macromol. 164: 2418-2431. PMID: 32798544
- [Clinical experience of sisomicin sulfate by intravenous drip infusion for the treatment of infection complicated by malignant disease]. | Tamura, K., et al. 1984. Jpn J Antibiot. 37: 1237-40. PMID: 6593472
- Forensic investigation of gentamicin sulfates by anion-exchange ion chromatography with pulsed electrochemical detection. | Kaine, LA. and Wolnik, KA. 1994. J Chromatogr A. 674: 255-61. PMID: 8075773
- In vitro susceptibility of gentamicin-resistant Enterobacteriaceae and Pseudomonas aeruginosa to netilmicin and selected aminoglycoside antibiotics. | Meyer, RD., et al. 1976. Antimicrob Agents Chemother. 10: 677-81. PMID: 825036
- Multi-residue determination of twenty aminoglycoside antibiotics in various food matrices by dispersive solid phase extraction and liquid chromatography-tandem mass spectrometry | Yu Ra Kim, Hui-Seung Kang. 2021. Food Control. 130.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sisomicin sulfate salt, 250 mg | sc-236885 | 250 mg | $90.00 | |||
Sisomicin sulfate salt, 1 g | sc-236885A | 1 g | $303.00 |