Date published: 2026-4-4

1-800-457-3801

SCBT Portrait Logo
Seach Input

SIRT1/2 Inhibitor IV, Cambinol (CAS 14513-15-6)

5.0(1)
Write a reviewAsk a question

See product citations (4)

Alternate Names:
5-(2-Hydroxynaphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
Application:
SIRT1/2 Inhibitor IV, Cambinol is an inhibitor of SIRT1, SIRT2, and SIRT5
CAS Number:
14513-15-6
Purity:
>95%
Molecular Weight:
360.43
Molecular Formula:
C21H16N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

SIRT1/2 Inhibitor IV, Cambinol is known as an inhibitor of sirtuin enzymes SIRT1 and SIRT2, which are involved in deacetylation of proteins that contribute to epigenetic regulation and post-translational modifications. Research employing SIRT1/2 Inhibitor IV, Cambinol is focused on elucidating the role of sirtuins in cellular processes such as aging, gene expression, and the stress response. By inhibiting SIRT1 and SIRT2, SIRT1/2 Inhibitor IV, Cambinol allows scientists to study the consequences of reduced sirtuin activity and its impact on cell function and survival. This compound is useful in investigating the potential of sirtuins as targets for modulating pathways implicated in longevity and age-associated diseases. Additionally, SIRT1/2 Inhibitor IV, Cambinol is employed in research to explore the effects of sirtuin inhibition on tumor growth and proliferation, providing insights into the mechanisms by which these enzymes influence cellular transformation and stability.


SIRT1/2 Inhibitor IV, Cambinol (CAS 14513-15-6) References

  1. Current advances in the synthesis and antitumoral activity of SIRT1-2 inhibitors by modulation of p53 and pro-apoptotic proteins.  |  Botta, G., et al. 2012. Curr Med Chem. 19: 5871-84. PMID: 22998567

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

SIRT1/2 Inhibitor IV, Cambinol, 5 mg

sc-204280
5 mg
$145.00