Molecular structure of Sipholenol A, CAS Number: 78518-73-7
Sipholenol A (CAS 78518-73-7)
Alternate Names:
(3R,5aR,6R,7S,9aR)-6-[2-[(1R,3aR,5S,8aR)-1-hydroxy-1,4,4, 6-tetramethyl-2,3,3a,5,8,8a-hexahydroazulen-5-yl]ethyl]-2,2,5a, 7-tetramethyl-4,5,6,8,9,9a-hexahydro-3H-benzo[b]oxepine-3,7-diol
Application:
Sipholenol A is an inhibitor of Mdr (P-glycoprotein; Pgp) function
CAS Number:
78518-73-7
Molecular Weight:
476.73
Molecular Formula:
C30H52O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Sipholenol A efficiently inhibits the function of P-glycoprotein (Pgp). It is a new reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. This has antiproliferative activity, and is cytotoxic.
Sipholenol A (CAS 78518-73-7) References
S. Carmely & Y. Kashman; J. Org. Chem. 48, 3517 (1983). S. Jain, et al.; J. Nat. Prod. 70, 928 (2007). Z. Shi, et al.; Cancer Sci. 98, 1373 (2007). S. Jain, et al.; Planta Med. 73, 591 (2007).Inhibitor of:
Mdr-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sipholenol A, 100 µg | sc-222313 | 100 µg | $200.00 |