Date published: 2025-9-5

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Silicon dioxide (CAS 14808-60-7)

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Alternate Names:
Silica
Application:
Silicon dioxide is a finely ground SiO2 preparation known as Amorphous
CAS Number:
14808-60-7
Purity:
99%
Molecular Weight:
60.08
Molecular Formula:
SiO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Silicon dioxide, commonly known as silica, serves as a fundamental component in scientific research across numerous disciplines due to its diverse properties and versatile applications. One of its primary mechanisms of action lies in its role as a desiccant and adsorbent. Silicon dioxide′s high surface area and affinity for water molecules make it invaluable in research settings for the drying and purification of solvents, gases, and biological samples. Furthermore, silica finds extensive use as a stationary phase in chromatography, where it facilitates the separation and purification of complex mixtures based on differences in polarity, size, and interactions with the silica surface. Its compatibility with various mobile phases and its tunable surface properties make it suitable for a wide range of chromatographic techniques, including thin-layer chromatography (TLC), column chromatography, and high-performance liquid chromatography (HPLC). Additionally, silicon dioxide plays a crucial role in materials science and nanotechnology, where it serves as a precursor for the synthesis of silica nanoparticles and the fabrication of silica-based materials with tailored properties for applications in catalysis, sensing, and drug delivery. Moreover, research efforts have explored its potential in biotechnology, where silica-based materials are employed in biosensing platforms, biomolecule immobilization, and tissue engineering scaffolds. Overall, silicon dioxide continues to be a cornerstone in scientific investigations, owing to its diverse functionalities and broad utility in research applications spanning chemistry, materials science, nanotechnology, and biotechnology.


Silicon dioxide (CAS 14808-60-7) References

  1. Effect of silicon dioxide on expression of poly (ADP-ribose) polymerase mRNA and protein.  |  Gao, A., et al. 2009. Cell Biol Int. 33: 749-54. PMID: 19393750
  2. Effect of thin silicon dioxide layers on resonant frequency in infrared metamaterials.  |  Shelton, DJ., et al. 2010. Opt Express. 18: 1085-90. PMID: 20173930
  3. Silicon dioxide hollow microspheres with porous composite structure: synthesis and characterization.  |  Yan, X. and Lei, Z. 2011. J Colloid Interface Sci. 362: 253-60. PMID: 21788029
  4. Application of mesoporous silicon dioxide and silicate in oral amorphous drug delivery systems.  |  Qian, KK. and Bogner, RH. 2012. J Pharm Sci. 101: 444-63. PMID: 21976048
  5. Raman spectra of high- κ dielectric layers investigated with micro-Raman spectroscopy comparison with silicon dioxide.  |  Borowicz, P., et al. 2013. ScientificWorldJournal. 2013: 208081. PMID: 24072982
  6. Toxic Effects of Nanostructured Silicon Dioxide on Multipotent Mesenchymal Stromal Cells.  |  Lykov, AP., et al. 2017. Bull Exp Biol Med. 163: 159-162. PMID: 28577099
  7. An Enhanced Soft Vibrotactile Actuator Based on ePVC Gel with Silicon Dioxide Nanoparticles.  |  Park, WH., et al. 2018. IEEE Trans Haptics. 11: 22-29. PMID: 29611810
  8. Microorganism adhesion using silicon dioxide: An experimental study.  |  Lozins, R., et al. 2020. Heliyon. 6: e03678. PMID: 32280796
  9. Determination of Two Differently Manufactured Silicon Dioxide Nanoparticles by Cloud Point Extraction Approach in Intestinal Cells, Intestinal Barriers and Tissues.  |  Yoo, NK., et al. 2021. Int J Mol Sci. 22: PMID: 34210022
  10. Nanosized Additives: Silicon Dioxide's Potential Role in Development of Food Sensitivities in Mice.  |  Schmidt, S. 2024. Environ Health Perspect. 132: 54003. PMID: 38814861

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Silicon dioxide, 100 g

sc-203376
100 g
$80.00

Silicon dioxide, 500 g

sc-203376A
500 g
$100.00

Silicon dioxide, 1 kg

sc-203376B
1 kg
$155.00