Date published: 2026-9-10

1-800-457-3801

SCBT Portrait Logo
Seach Input

Sialyllacto-N-tetraose b (CAS 64003-54-9)

0.0(0)
Write a reviewAsk a question

Alternate Names:
LS-tetrasaccharide b; N-Acetylneuraminyllacto-N-tetraose b
CAS Number:
64003-54-9
Molecular Weight:
998.88
Molecular Formula:
C37H62N2O29
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Sialyllacto-N-tetraose b is a specialized oligosaccharide not found in naturally occurring proteins. In research applications, this chemical′s unique structure is used to probe the conformational stability of peptides and proteins. Scientists utilize it to synthesize peptidomimetics, which are compounds that mimic the structure of peptides and can provide insight into protein folding and stability. Due to its bicyclic structure, Sialyllacto-N-tetraose b introduces conformational constraints when incorporated into peptides, which is invaluable for structure-activity relationship studies. Additionally, its incorporation into peptide chains can help in the study of protein-protein interactions, a critical aspect of understanding cellular processes at the molecular level.


Sialyllacto-N-tetraose b (CAS 64003-54-9) References

  1. High-performance capillary electrophoresis of sialylated oligosaccharides of human milk.  |  Shen, Z., et al. 2000. Anal Biochem. 279: 37-45. PMID: 10683228
  2. Quantitative analysis of human milk oligosaccharides by capillary electrophoresis.  |  Newburg, DS., et al. 2000. Adv Exp Med Biol. 478: 381-2. PMID: 11065092
  3. Resolution of structural isomers of sialylated oligosaccharides by capillary electrophoresis.  |  Shen, Z., et al. 2001. J Chromatogr A. 921: 315-21. PMID: 11471815
  4. The sialylated fraction of milk oligosaccharides is partially responsible for binding to enterotoxigenic and uropathogenic Escherichia coli human strains.  |  Martín-Sosa, S., et al. 2002. J Nutr. 132: 3067-72. PMID: 12368397
  5. Sialyloligosaccharides in human and bovine milk and in infant formulas: variations with the progression of lactation.  |  Martín-Sosa, S., et al. 2003. J Dairy Sci. 86: 52-9. PMID: 12613848
  6. Simultaneous quantification of sialyloligosaccharides from human milk by capillary electrophoresis.  |  Bao, Y., et al. 2007. Anal Biochem. 370: 206-14. PMID: 17761135
  7. Determination of sialyl and neutral oligosaccharide levels in transition and mature milks of Samoan women, using anthranilic derivatization followed by reverse phase high performance liquid chromatography.  |  Leo, F., et al. 2010. Biosci Biotechnol Biochem. 74: 298-303. PMID: 20139617
  8. Structures of receptor complexes of a North American H7N2 influenza hemagglutinin with a loop deletion in the receptor binding site.  |  Yang, H., et al. 2010. PLoS Pathog. 6: e1001081. PMID: 20824086
  9. Preterm milk oligosaccharides during the first month of lactation.  |  Gabrielli, O., et al. 2011. Pediatrics. 128: e1520-31. PMID: 22123889
  10. The human milk oligosaccharide disialyllacto-N-tetraose prevents necrotising enterocolitis in neonatal rats.  |  Jantscher-Krenn, E., et al. 2012. Gut. 61: 1417-25. PMID: 22138535
  11. Liquid chromatography/tandem mass spectrometry with fluorous derivatization method for selective analysis of sialyl oligosaccharides.  |  Sakaguchi, Y., et al. 2014. Rapid Commun Mass Spectrom. 28: 2481-9. PMID: 25366395
  12. Human Milk Oligosaccharides (HMOS): Structure, Function, and Enzyme-Catalyzed Synthesis.  |  Chen, X. 2015. Adv Carbohydr Chem Biochem. 72: 113-90. PMID: 26613816
  13. Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection.  |  Ramani, S., et al. 2018. Nat Commun. 9: 5010. PMID: 30479342
  14. Comparative Analysis of Oligosaccharides in Breast Milk and Feces of Breast-Fed Infants by Using LC-QE-HF-MS: A Communication.  |  Li, R., et al. 2023. Nutrients. 15: PMID: 36839244

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sialyllacto-N-tetraose b, 500 µg

sc-286773
500 µg
$872.00

Sialyllacto-N-tetraose b, 1 mg

sc-286773A
1 mg
$1358.00