SHP-77 Whole Cell Lysate: sc-364258
- 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
- human whole cell lysate; pulmonary small cell carcinoma cells
- whole cell lysate provided as Western blotting positive control
- should be stored at -20°C and repeated freezing and thawing should be minimized
- sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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SHP-77 whole cell lysate is derived from the SHP-77 cell line, which originates from a non-encapsulated primary lung tumor from the apical portion of the upper lobe of the left lung. This lysate provides a valuable resource for examining the molecular characteristics and behavior of SCLC under various experimental conditions. Researchers utilize SHP-77 lysate to study the mechanisms of action of key oncogenic drivers in SCLC, including abnormalities in the expression of MYC oncogenes and disruptions in the p53 and RB1 tumor suppressor pathways, which are frequently altered in this cancer type. The lysate allows for the exploration of cellular responses to DNA damage and the efficacy of DNA repair mechanisms, as well as the regulation of apoptosis and cell cycle progression in cancer cells. Additionally, SHP-77 cell lysate is used to investigate the impact of environmental factors and chemical compounds on gene expression and signal transduction pathways that influence tumor growth and cell survival. Through these studies, SHP-77 lysate aids in advancing the understanding of the cellular and molecular basis of SCLC.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SHP-77 Whole Cell Lysate | sc-364258 | 500 µg/200 µl | $118.00 |