SHIP-1 Antibody (G-11): sc-271203
- SHIP-1 Antibody (G-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 1-105 mapping at the N-terminus of SHIP-1 of mouse origin
- recommended for detection of SHIP-1 p145 of mouse, rat and human origin by WB, IP, IF and ELISA
- See SHIP-1 (P1C1): sc-8425 for SHIP-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SHIP-1 Antibody (G-11) for WB applications. These reagents are now offered in bundles with SHIP-1 Antibody (G-11) (see ordering information below).
SHIP-1 Antibody (G-11) is a mouse monoclonal IgG2b kappa light chain antibody engineered to detect SHIP-1, also known as INPP5D, across mouse, rat, and human species. SHIP-1 is a critical inositol phosphatase predominantly located in the cytoplasm and membrane regions of hematopoietic cells, where SHIP-1 plays a vital role in regulating the PI3K signaling pathway by dephosphorylating PIP3 to PIP2. This regulation is essential for controlling immune cell activation, proliferation, and survival, thereby maintaining immune homeostasis and preventing excessive immune responses that can lead to autoimmune disorders. Anti-SHIP-1 antibody (G-11) specifically targets the N-terminal epitope of SHIP-1, encompassing amino acids 1-105, which ensures high specificity and reliable performance in various applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). By enabling precise detection of SHIP-1 p145 across multiple species, SHIP-1 monoclonal antibody (G-11) serves as an invaluable tool for researchers investigating signal transduction, hematopoiesis, and immune responses. Anti-SHIP-1 antibody (G-11) reliably identifies SHIP-1 and facilitates comprehensive studies on SHIP-1′s function and regulation, contributing to a deeper understanding of SHIP-1′s role in various diseases and the development of targeted therapeutic strategies. SHIP-1 (G-11) monoclonal antibody provides consistent and accurate results, supporting advancements in the exploration of SHIP-1 mediated pathways and interactions within the cellular environment.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SHIP-1 Antibody (G-11) | sc-271203 | 200 µg/ml | $316.00 | |||
SHIP-1 Antibody (G-11): m-IgG Fc BP-HRP Bundle | sc-537588 | 200 µg Ab; 10 µg BP | $354.00 | |||
SHIP-1 Antibody (G-11): m-IgGκ BP-HRP Bundle | sc-534894 | 200 µg Ab; 40 µg BP | $354.00 |