Date published: 2026-4-26

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Setomimycin (CAS 69431-87-4)

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Alternate Names:
Setomimicin; AM-2947
Application:
Setomimycin is an antibiotic that is active against Gram positive bacteria, including mycobacteria
CAS Number:
69431-87-4
Molecular Weight:
580.58
Molecular Formula:
C34H28O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Setomimycin is a 9,9`-Bianthryl polyketide derivative. It is an antibiotic that is active against Gram positive bacteria, including mycobacteria. It is an inhibitor of bacterial cell wall synthesis. Setomimycin is an anti-tumor compound.


Setomimycin (CAS 69431-87-4) References

  1. Regio- and stereoselective intermolecular oxidative phenol coupling in Streptomyces.  |  Präg, A., et al. 2014. J Am Chem Soc. 136: 6195-8. PMID: 24746278
  2. Discovery of a Fungal Multicopper Oxidase That Catalyzes the Regioselective Coupling of a Tricyclic Naphthopyranone To Produce Atropisomers.  |  Kawaguchi, M., et al. 2018. Angew Chem Int Ed Engl. 57: 5115-5119. PMID: 29468784
  3. Huanglongmycin A-C, Cytotoxic Polyketides Biosynthesized by a Putative Type II Polyketide Synthase From Streptomyces sp. CB09001.  |  Jiang, L., et al. 2018. Front Chem. 6: 254. PMID: 30013965
  4. Characterisation of Two Polyketides from Streptomyces sp. SKH1-2 Isolated from Roots of Musa (ABB) cv. 'Kluai Sao Kratuep Ho'.  |  Kuncharoen, N., et al. 2019. Int Microbiol. 22: 451-459. PMID: 30941598
  5. Genome Analysis of Streptomyces nojiriensis JCM 3382 and Distribution of Gene Clusters for Three Antibiotics and an Azasugar across the Genus Streptomyces.  |  Park, JS., et al. 2021. Microorganisms. 9: PMID: 34576698
  6. Isolation and anticancer activity evaluation of rare Bisaryl anthraquinone antibiotics from novel Streptomyces sp. strain of NW Himalayan region.  |  Manhas, RS., et al. 2022. Chem Biol Interact. 365: 110093. PMID: 35985519
  7. A biostatistical approach for augmenting rare bianthraquinone antibiotic production by Streptomyces sp. RA-WS2 using Taguchi design.  |  Manhas, RS., et al. 2022. AMB Express. 12: 155. PMID: 36515787
  8. Identification and taxonomy of Streptomyces justiciae strain RA-WS2: a novel setomimycin producing actinobacterium.  |  Manhas, RS., et al. 2023. 3 Biotech. 13: 47. PMID: 36643399
  9. A new antibiotic, setomimycin, produced by a strain of Streptomyces.  |  Omura, S., et al. 1978. J Antibiot (Tokyo). 31: 1091-8. PMID: 721705
  10. Stereocontrolled total synthesis of an. alpha.-methylene guaianolide in the 4, 5-epoxyosmitopsin family.  |  Posner, Gary H., et al. 1980. Journal of the American Chemical Society. 102.25: 7498-7505.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Setomimycin, 1 mg

sc-396560
1 mg
$158.00

Setomimycin, 5 mg

sc-396560A
5 mg
$617.00