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Serotonin O-Sulfate (CAS 16310-20-6)

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Alternate Names:
3-(2-Aminoethyl)-1H-indol-5-ol 5-(Hydrogen Sulfate); 5-Hydroxytryptamine O-sulfate; 5-Hydroxytryptamine Sulfate
Application:
Serotonin O-Sulfate is A metabolite of Serotonin (5-hydroxytryptamine, 5-HT)
CAS Number:
16310-20-6
Molecular Weight:
256.28
Molecular Formula:
C10H12N2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Serotonin O-sulfate, also known as 5-hydroxytryptamine-O-sulfate or 5-HT-O-S, holds a significant position as an essential metabolite of serotonin. Serotonin, a neurotransmitter,undergoes transformation to produce this important compound. The enzyme 5Serotonin O-sulfate (5-HT-OST) facilitates its formation, playing a role in various biochemical processes. Moreover, serotonin O-sulfate serves as a key intermediate in the metabolism of serotonin and other neurotransmitters. The precise mechanism of action of serotonin O-sulfate is not fully elucidated. However, it is believed to function as a regulator of the serotonin system by modulating the activity of serotonin receptors. Additionally, it has been suggested that serotonin O-sulfate may act as a modulator of the serotonin transporter, responsible for the uptake of serotonin.


Serotonin O-Sulfate (CAS 16310-20-6) References

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  2. Serotonin catabolism depends upon location of release: characterization of sulfated and gamma-glutamylated serotonin metabolites in Aplysia californica.  |  Stuart, JN., et al. 2003. J Neurochem. 84: 1358-66. PMID: 12614336
  3. Synthesis and properties of serotonin O-sulfate.  |  KISHIMOTO, Y., et al. 1961. J Biochem. 49: 436-40. PMID: 13756366
  4. Recent advances in the application of capillary electrophoresis to neuroscience.  |  Powell, PR. and Ewing, AG. 2005. Anal Bioanal Chem. 382: 581-91. PMID: 15726336
  5. Contributions of capillary electrophoresis to neuroscience.  |  Lapainis, T. and Sweedler, JV. 2008. J Chromatogr A. 1184: 144-58. PMID: 18054026
  6. Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations.  |  Gabrielsen, M., et al. 2012. J Mol Model. 18: 1073-85. PMID: 21670993
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  8. Immunomodulatory effects mediated by serotonin.  |  Arreola, R., et al. 2015. J Immunol Res. 2015: 354957. PMID: 25961058
  9. Formation of serotonin O-sulfate by sulfotransferase of rabbit liver.  |  Hidaka, H., et al. 1969. Biochim Biophys Acta. 177: 354-7. PMID: 5780096
  10. Isolation of serotonin-O-sulfate from human urine.  |  Davis, VE., et al. 1966. Clin Chim Acta. 13: 380-2. PMID: 5943828
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Serotonin O-Sulfate, 5 mg

sc-208385
5 mg
$388.00