Septin 10 Antibody (D-9): sc-365774

Septin 10 Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects Septin 10 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Septin 10 is a 517-residue polypeptide that plays a crucial role in various cellular processes, including cytokinesis and the organization of cellular structures. Septin 10 is primarily localized in the cytoplasm and nucleus, which is significant as presence in these compartments is essential for function in cell division and maintaining cellular integrity. Septin 10 is expressed ubiquitously, with highest levels found in the placenta, lung, kidney, heart, skeletal muscles, liver, and various tumor cell lines, indicating importance in both normal physiology and disease states. Notably, Septin 10 exhibits GTP-binding and GTPase activity, characteristics vital for forming heteropolymer complexes with other septins, thereby contributing to dynamic organization of the cytoskeleton. Furthermore, Septin 10 expression is upregulated in dendritic cells upon maturation induced by lipopolysaccharide, highlighting potential involvement in immune responses. Anti-Septin 10 antibody (D-9) is an invaluable tool for researchers studying the intricate roles of septins in cellular processes and their implications in various diseases.

The preferred Septin 10 antibody is Septin 10 Antibody (A-2): sc-365775.