Date published: 2025-10-2

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Senecionine-D3 (CAS 130-01-8 (unlabeled))

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Alternate Names:
Aureine-D3
CAS Number:
130-01-8 (unlabeled)
Molecular Weight:
338.41
Molecular Formula:
C18H22D3NO5
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Senecionine-D3 functions as a potent alkaloid toxin. It interacts with cellular components by targeting and binding to certain receptors or enzymes within the cell. This binding triggers a cascade of molecular events that disrupt normal cellular processes, leading to cellular dysfunction and ultimately cell death. Senecionine-D3 interferes with key cellular pathways, such as protein synthesis and DNA replication, by inhibiting the activity of essential enzymes involved in these processes. It can disrupt cellular signaling pathways, leading to aberrant cellular responses and dysfunction. Senecionine-D3 also has the ability to induce oxidative stress within the cell, leading to damage to cellular components such as proteins, lipids, and DNA. Senecionine-D3 exerts its toxic effects by interfering with essential cellular processes and pathways, ultimately leading to cellular dysfunction and death.


Senecionine-D3 (CAS 130-01-8 (unlabeled)) References

  1. Intrinsic relative potency of a series of pyrrolizidine alkaloids characterized by rate and extent of metabolism.  |  Lester, C., et al. 2019. Food Chem Toxicol. 131: 110523. PMID: 31129256
  2. In-house validation and application of UHPLC-MS/MS method for the quantification of pyrrolizidine and tropane alkaloids in commercial honey bee-collected pollen, teas and herbal infusions purchased on Italian market in 2019–2020 referring to recent European Union regulations  |  Marianna Martinello, Chiara Manzinello, Albino Gallina, Franco Mutinelli. 2022. International Journal of Food Science & Technology. Volume57, Issue12: 7505-7516.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Senecionine-D3, 250 µg

sc-473324
250 µg
$1638.00